INT36354

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Context Info
Confidence 0.64
First Reported 1987
Last Reported 2009
Negated 0
Speculated 2
Reported most in Body
Documents 26
Total Number 30
Disease Relevance 20.84
Pain Relevance 9.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
tendon 3
nerve 3
ligament 2
wrist 2
muscles 1
CTs (Homo sapiens)
Pain Link Frequency Relevance Heat
carpal tunnel syndrome 297 100.00 Very High Very High Very High
complementary and alternative medicine 139 99.92 Very High Very High Very High
peripheral neuropathy 2 98.76 Very High Very High Very High
rheumatoid arthritis 8 98.16 Very High Very High Very High
imagery 91 93.96 High High
Paresthesia 7 88.84 High High
Pain 46 88.20 High High
Sciatica 1 84.12 Quite High
fibrosis 8 82.40 Quite High
Neurolysis 4 65.12 Quite High
Disease Link Frequency Relevance Heat
Carpal Tunnel Syndrome 395 100.00 Very High Very High Very High
Injury 12 99.98 Very High Very High Very High
Recurrence 12 99.60 Very High Very High Very High
Diabetes Mellitus 6 99.60 Very High Very High Very High
Congenital Anomalies 6 99.30 Very High Very High Very High
Mucopolysaccharidoses 3 99.06 Very High Very High Very High
Thyroid Disease 9 98.84 Very High Very High Very High
Peripheral Neuropathy 2 98.76 Very High Very High Very High
Contusions 1 98.22 Very High Very High Very High
Rheumatoid Arthritis 8 98.16 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients are excluded from the study if: 1) they have already been treated with a wrist splint or have had previous carpal tunnel release; 2) they have a history of wrist or median nerve injury from trauma (e.g. contusion, fractures) or prior surgery on the wrist; 3) they have a history suggesting underlying causes of CTS, such as diabetes mellitus, thyroid disease, rheumatoid arthritis, chronic renal failure treated by hemodialysis, space-occupying lesions in the volar wrist area, anatomic abnormalities of the wrist or hand, pregnancy or lactation; 4) they have clinical signs or symptoms, or electrodiagnostic studies suggesting conditions that could mimic CTS or interfere with its validation, such as cervical radiculopathy, brachial plexopathy, thoracic outlet syndrome, pronator teres syndrome, ulnar neuropathy, polyneuropathy, Raynaud's disease or sympathetic dystrophy; 5) there is severe thenar muscle atrophy.
Localization (causes) of CTS in wrist associated with chronic renal failure, syndrome, muscular atrophy, neuropathy, brachial plexus neuropathies, nerve root compression, nervous system injury, congenital anomalies, thyroid disease, thoracic outlet syndrome, diabetes mellitus, rheumatoid arthritis, sciatica, disease, injury, carpal tunnel syndrome, contusions and ulnar neuropathies
1) Confidence 0.64 Published 2001 Journal BMC Neurol Section Body Doc Link PMC64540 Disease Relevance 1.68 Pain Relevance 0.21
CONCLUSIONS: In our study, among a group of heavy labourers, no cases of CTS were detected.
Localization (cases) of CTS
2) Confidence 0.64 Published 2008 Journal Occup Med (Lond) Section Body Doc Link 18211908 Disease Relevance 0.07 Pain Relevance 0
METHODS: Reports from 3 sources were evaluated with regard to support for etiological theories of CTS: 1) patient-oriented information on CTS from the Internet, 2) recent physician-oriented information on CTS from medical journals indexed on Index Medicus, and 3) articles addressing the etiology of CTS from the 1997 National Institute for Occupational Safety and Health report.
Localization (etiology) of CTS
3) Confidence 0.64 Published 2008 Journal J Hand Surg Am Section Body Doc Link 18762100 Disease Relevance 0.09 Pain Relevance 0
METHODS: Reports from 3 sources were evaluated with regard to support for etiological theories of CTS: 1) patient-oriented information on CTS from the Internet, 2) recent physician-oriented information on CTS from medical journals indexed on Index Medicus, and 3) articles addressing the etiology of CTS from the 1997 National Institute for Occupational Safety and Health report.
Localization (information) of CTS
4) Confidence 0.64 Published 2008 Journal J Hand Surg Am Section Body Doc Link 18762100 Disease Relevance 0.09 Pain Relevance 0
PURPOSE: The purpose of this investigation was to extend the previously reported short-term randomized trial of open and endoscopic carpal tunnel release in patients with carpal tunnel syndrome (CTS) to compare outcomes 5 years after surgery.
Localization (release) of CTS associated with carpal tunnel syndrome
5) Confidence 0.64 Published 2009 Journal J Hand Surg Am Section Abstract Doc Link 19181226 Disease Relevance 0.27 Pain Relevance 0.10
Also we found that the severity of CTS or pain distribution in these patients was not related to the presence or absence of these tendons.


Localization (severity) of CTS in tendons
6) Confidence 0.64 Published 2009 Journal Eur. J. Neurol. Section Body Doc Link 19236463 Disease Relevance 0.06 Pain Relevance 0
RESULTS: Although moderate and severe CTS showed significant improvement in clinical parameters at 4 weeks and 2 months, EDX parameters of moderate CTS were significantly improved at 4 weeks, but diminished at 8 weeks.
Localization (severe) of CTS
7) Confidence 0.64 Published 2009 Journal Clin J Pain Section Body Doc Link 19333155 Disease Relevance 0.08 Pain Relevance 0
METHODS: Twenty five patients with signs and positive electromyographic of CTS were evaluated with ultrasound.
Localization (electromyographic) of CTS
8) Confidence 0.64 Published 2009 Journal Tunis Med Section Body Doc Link 19522430 Disease Relevance 0.10 Pain Relevance 0
METHODS: 206 patients with clinical features suggestive of carpal tunnel syndrome (CTS), including those with known underlying cause of CTS, were screened for thyroid dysfunction.
Localization (cause) of CTS in thyroid
9) Confidence 0.64 Published 2004 Journal J Clin Rheumatol Section Body Doc Link 17043482 Disease Relevance 0.19 Pain Relevance 0
Although flexor-retinaculum (FR) release provides dramatic relief from carpal tunnel syndrome (CTS), the role of this ligament in CTS is not well understood.
Localization (release) of carpal tunnel syndrome in ligament associated with carpal tunnel syndrome
10) Confidence 0.61 Published 1996 Journal J. Occup. Environ. Med. Section Abstract Doc Link 8882098 Disease Relevance 0.67 Pain Relevance 0.67
Although flexor-retinaculum (FR) release provides dramatic relief from carpal tunnel syndrome (CTS), the role of this ligament in CTS is not well understood.
Localization (release) of CTS in ligament associated with carpal tunnel syndrome
11) Confidence 0.61 Published 1996 Journal J. Occup. Environ. Med. Section Abstract Doc Link 8882098 Disease Relevance 0.67 Pain Relevance 0.67
An overview is presented of the assessment of carpal tunnel syndrome (CTS) in manual workers, with emphasis on the distinction from other compression syndromes and from diffuse polyneuropathy.
Localization (presented) of CTS associated with neuropathy, syndrome and carpal tunnel syndrome
12) Confidence 0.61 Published 1987 Journal Scand J Work Environ Health Section Abstract Doc Link 3324318 Disease Relevance 0.47 Pain Relevance 0.34
All patients were subjected to a decompression procedure of the median nerve and postoperative alleviation of the symptoms was considered as confirmation of the presence of a CTS.
Localization (presence) of CTS in median nerve
13) Confidence 0.61 Published 2007 Journal Minim Invasive Neurosurg Section Body Doc Link 18210354 Disease Relevance 0.08 Pain Relevance 0
To examine this premise, we used Bureau of Labor Statistics injury counts (numerator) and census data from the Current Population Survey (denominator) to determine injury rates of CTS for both men and women in six high-risk occupations: (1) assembler, (2) laborer-nonconstruction, (3) packaging and filling machine operators, (4) janitors and cleaners, (5) butchers and meat cutters, and (6) data entry keyers.
Spec (determine) Localization (rates) of CTS associated with injury and carpal tunnel syndrome
14) Confidence 0.61 Published 2000 Journal Environ. Res. Section Abstract Doc Link 10845778 Disease Relevance 1.15 Pain Relevance 0.80
METHODS: At 1.5 T, 41 wrists in 37 patients with previous CTS release were evaluated by two observers for 1) flexor retinacular regrowth; 2) median nerve: a) high T2 signal, b) proximal enlargement, c) fibrous fixation, d) neuroma, and e) entrapment; 3) flexor tenosynovitis; 4) mass, bursitis, accessory muscle, distal belly progression, or excessive deep fat; 5) hamate fracture; and 6) volar nerve migration.
Localization (release) of CTS in fat
15) Confidence 0.61 Published 2004 Journal J Comput Assist Tomogr Section Body Doc Link 15538166 Disease Relevance 0.10 Pain Relevance 0
INTERVENTIONS: All patients underwent surgical release of CTS by the mini-incision of palm technique.
Localization (release) of CTS
16) Confidence 0.61 Published 2004 Journal Arch Phys Med Rehabil Section Body Doc Link 14970961 Disease Relevance 0.26 Pain Relevance 0
In Mucopolysaccharidoses, prospective studies (Wraith and Alani, 1990) found a bilateral CTS in about 90%.
Localization (found) of CTS associated with mucopolysaccharidoses and carpal tunnel syndrome
17) Confidence 0.61 Published 1994 Journal Electromyogr Clin Neurophysiol Section Abstract Doc Link 7882890 Disease Relevance 1.12 Pain Relevance 0.43
CONCLUSION: Open surgical release of CTS provides favorable results that can be sufficiently evaluated by the clinical scoring system alone.
Localization (release) of CTS
18) Confidence 0.61 Published 2002 Journal Acta Orthop Traumatol Turc Section Body Doc Link 12510085 Disease Relevance 0 Pain Relevance 0
This pilot evaluation of 17 subjects with CTS involved the same battery completed twice prior to CTS release.
Localization (release) of CTS associated with carpal tunnel syndrome
19) Confidence 0.61 Published 1999 Journal J Hand Ther Section Abstract Doc Link 10622198 Disease Relevance 0.63 Pain Relevance 0.48
Exclusion criteria are prior CTS release on the involved hand; diffuse peripheral neuropathy, any known mass, tumor or deformity; any history of severe trauma to the wrist (such as fracture); a deformity of the study hand; and pregnant or lactating (table 1).
Localization (release) of CTS in wrist associated with cancer, injury, carpal tunnel syndrome and peripheral neuropathy
20) Confidence 0.55 Published 2005 Journal BMC Musculoskelet Disord Section Body Doc Link PMC546190 Disease Relevance 1.11 Pain Relevance 0.51

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