INT36404

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Context Info
Confidence 0.62
First Reported 1980
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 1.38
Pain Relevance 3.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GAST) extracellular region (GAST)
Anatomy Link Frequency
capsule 2
gastric juice 2
gut 2
fat 1
gum 1
GAST (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 16 100.00 Very High Very High Very High
opiate 7 100.00 Very High Very High Very High
narcan 7 100.00 Very High Very High Very High
Morphine 5 100.00 Very High Very High Very High
antagonist 4 100.00 Very High Very High Very High
peptic ulcer disease 2 92.40 High High
Somatostatin 1 88.84 High High
Calcitonin gene-related peptide 1 81.88 Quite High
agonist 2 77.52 Quite High
Paracetamol 1 74.32 Quite High
Disease Link Frequency Relevance Heat
Ulcers 9 91.96 High High
Duodenal Ulcer 3 89.28 High High
Anxiety Disorder 31 86.56 High High
Gastric Motility Disorder 1 72.76 Quite High
Pneumonia 7 60.32 Quite High
Disease 2 53.44 Quite High
Vomiting 1 50.00 Quite Low
Hyperplasia 1 36.68 Quite Low
Stress 2 31.68 Quite Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of a synthetic met-enkephalin analogue (FK 33-824) on gastric acid secretion and serum gastrin in man.
Regulation (effect) of Localization (secretion) of gastrin associated with enkephalin
1) Confidence 0.62 Published 1981 Journal Scand. J. Gastroenterol. Section Title Doc Link 7323691 Disease Relevance 0 Pain Relevance 0.77
A chilli-rich diet had an inhibitory effect on gastrin release upon stimulation compared to the results that were obtained before the start of the diet.
Regulation (effect) of Localization (release) of gastrin
2) Confidence 0.60 Published 2009 Journal Dig. Dis. Sci. Section Body Doc Link 18668366 Disease Relevance 0 Pain Relevance 0
These studies demonstrate that a placebo capsule, administered by a physician just prior to a meal, has little, if any, effect on acid secretion or gastrin release in response to the meal.
Neg (little) Regulation (effect) of Localization (secretion) of gastrin in capsule
3) Confidence 0.45 Published 1988 Journal Dig. Dis. Sci. Section Abstract Doc Link 3338362 Disease Relevance 0.32 Pain Relevance 0.09
Effect of naloxone and morphine on gastric acid secretion and on serum gastrin and pancreatic polypeptide concentrations in humans.
Regulation (Effect) of Localization (secretion) of gastrin associated with narcan and morphine
4) Confidence 0.45 Published 1980 Journal Gastroenterology Section Title Doc Link 7399233 Disease Relevance 0.07 Pain Relevance 1.04
These findings suggest that plaunotol may suppress hypergastrinemia induced by long-term omeprazole administration, at least partly, via a certain brain-gut hormone affecting gastrin release.
Regulation (affecting) of Localization (release) of gastrin in gut
5) Confidence 0.44 Published 1995 Journal Dig. Dis. Sci. Section Abstract Doc Link 7821104 Disease Relevance 0.55 Pain Relevance 0.14
In our results, however, we could not detect any differences in serum gastrin concentration which has been known as a major hormone regulating secretion of gastric juice.
Regulation (regulating) of Localization (secretion) of gastrin in gastric juice
6) Confidence 0.44 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2808598 Disease Relevance 0.43 Pain Relevance 0
Effect of oral nalmefene, an opiate-receptor antagonist, on meal-stimulated gastric acid secretion and serum gastrin concentration in man.
Regulation (Effect) of Localization (secretion) of gastrin associated with antagonist and opiate
7) Confidence 0.27 Published 1985 Journal Regul. Pept. Section Title Doc Link 4059587 Disease Relevance 0 Pain Relevance 0.39
A synthetic met-enkephalin analogue was infused into seven healthy human subjects on a background infusion of pentagastrin to study the effect on gastric acid secretion and serum gastrin concentration.
Regulation (effect) of Localization (secretion) of gastrin associated with enkephalin
8) Confidence 0.27 Published 1981 Journal Scand. J. Gastroenterol. Section Abstract Doc Link 7323691 Disease Relevance 0 Pain Relevance 0.53
The effect of incorporating guar gum into predominantly single-component meals of carbohydrate, fat or protein on liquid gastric emptying and on the secretion of gastric inhibitory polypeptide (GIP), gastrin and motilin, was studied in healthy human volunteers.
Regulation (effect) of in fat Localization (secretion) of gastrin in gum
9) Confidence 0.21 Published 1985 Journal Br. J. Nutr. Section Abstract Doc Link 4063284 Disease Relevance 0 Pain Relevance 0.07

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