INT36411

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Context Info
Confidence 0.03
First Reported 1988
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 3.50
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ecg2)
Anatomy Link Frequency
blood 1
chest 1
rib 1
Ecg2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 1 99.02 Very High Very High Very High
Angina 10 95.60 Very High Very High Very High
imagery 15 86.80 High High
ischemia 23 50.00 Quite Low
anesthesia 2 26.56 Quite Low
depression 9 5.00 Very Low Very Low Very Low
aspirin 6 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 305 99.58 Very High Very High Very High
Pain 1 99.02 Very High Very High Very High
Rib Fractures 1 98.84 Very High Very High Very High
Contusions 9 98.14 Very High Very High Very High
Angina 10 95.60 Very High Very High Very High
Emergencies 6 94.68 High High
Injury 10 92.64 High High
Critical Illness 57 90.60 High High
Coronary Artery Disease 32 50.00 Quite Low
Bundle-branch Block 6 22.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Those with anterior chest wall contusions, sternal or anterior rib fractures, or pain/tenderness of the anterior chest (n = 140, 13%) underwent immediate and daily ECG, and CPK isoenzymes were measured at admission and every 6 hours in the first 24 hours.
Positive_regulation (underwent) of ECG in rib associated with pain, contusions and rib fractures
1) Confidence 0.03 Published 1988 Journal J Trauma Section Abstract Doc Link 3339663 Disease Relevance 1.04 Pain Relevance 0.10
DESIGN: In a prospective clinical study, we compared the diagnostic performances of clinical symptoms, presenting ECG, creatinine kinase, creatine kinase MB activity and mass concentration, myoglobin, and cardiac troponin T test results of hospital admission blood samples.
Positive_regulation (presenting) of ECG in blood
2) Confidence 0.01 Published 1995 Journal Chest Section Body Doc Link 7497751 Disease Relevance 0.28 Pain Relevance 0
A 12-hour diagnostic protocol included serial measurements of creatine kinase MB, ECG, and clinical assessments followed by ExECG for those with negative initial serial testing.
Positive_regulation (measurements) of ECG
3) Confidence 0.01 Published 1997 Journal Arch. Intern. Med. Section Body Doc Link 9164374 Disease Relevance 0 Pain Relevance 0
Key messages

• The diagnosis of MI in the ICU is usually dependent on elevated troponin levels and ischemic changes on a 12-lead ECG or a new wall motion abnormality on echocardiography, because ICU patients are usually unable to communicate chest pain symptoms as a result of administration of narcotics or sedatives, or decreased level of consciousness. • In this single centre cohort study, 47% of predominantly medical critically ill patients had at least one elevated troponin measurement, but only 26% of these patients had MI. • An elevated troponin level alone is not an independent predictor of ICU or hospital mortality. • Patients with MI had a significant twofold increase in risk for ICU and hospital mortality compared with patients without MI. • After adjusting for APACHE II score and inotrope or vasopressor use, development of MI in the ICU setting was an independent predictor of hospital mortality.


Positive_regulation (elevated) of ECG in chest associated with angina, critical illness and myocardial infarction
4) Confidence 0.01 Published 2005 Journal Crit Care Section Body Doc Link PMC1414005 Disease Relevance 0.94 Pain Relevance 0.18
Screening with troponin levels in the ICU should not be done in isolation because ECG is necessary to interpret abnormal levels.
Positive_regulation (necessary) of ECG
5) Confidence 0.01 Published 2005 Journal Crit Care Section Body Doc Link PMC1414005 Disease Relevance 0.59 Pain Relevance 0.08
Patients diagnosed with MI in the ICU based on elevated troponin levels and ischemic ECG changes had higher ICU and hospital mortality, and MI was independently predictive of hospital mortality.
Positive_regulation (elevated) of ECG associated with myocardial infarction
6) Confidence 0.01 Published 2005 Journal Crit Care Section Body Doc Link PMC1414005 Disease Relevance 0.64 Pain Relevance 0

General Comments

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