INT36552

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 1988
Last Reported 1999
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GGT1) plasma membrane (GGT1) transferase activity, transferring acyl groups (GGT1)
cellular amino acid metabolic process (GGT1)
Anatomy Link Frequency
brush 2
urine 2
GGT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 11 99.44 Very High Very High Very High
Chronic pancreatitis 1 92.36 High High
Analgesic 1 41.16 Quite Low
Disease Link Frequency Relevance Heat
Pancreatitis 3 100.00 Very High Very High Very High
Nephrotoxicity 1 96.04 Very High Very High Very High
Renal Disease 8 95.32 Very High Very High Very High
Pancreatic Cancer 1 93.84 High High
Balkan Nephropathy 6 88.20 High High
Disorders Of Creatine Metabolism 1 59.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to investigate the role of renal factors in affecting trypsinogen 1 metabolism and excretion in chronic pancreatic disease, serum immunoreactive trypsin (IRT), urinary IRT, gamma-glutamyltransferase (GGT), alpha-glucosidase (AGL) and RNase outputs and the molecular size distribution of serum and urine IRT were studied in 8 control subjects, 18 cases with pancreatic cancer, and 23 cases with chronic pancreatitis.
Regulation (affecting) of Gene_expression (metabolism) of GGT in urine associated with pancreatic cancer, pancreatitis and chronic pancreatitis
1) Confidence 0.44 Published 1988 Journal Pancreas Section Abstract Doc Link 3362841 Disease Relevance 0.42 Pain Relevance 0.09
This study has shown that urinary excretion of APN, DPP IV, NAGA and GGT, as markers of kidney brush border and lysosomal damage, did not change after 2 g of acetaminophen taken orally. beta 2-microglobulin was a marker of acute acetaminophen nephrotoxicity in kidney disease patients and in clinically healthy adults from nephropathic families.
Neg (not) Regulation (change) of Gene_expression (excretion) of GGT in brush associated with nephrotoxicity, paracetamol and renal disease
2) Confidence 0.44 Published 1999 Journal Ren Fail Section Abstract Doc Link 10516997 Disease Relevance 0.87 Pain Relevance 0.78

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox