INT36556

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Context Info
Confidence 0.21
First Reported 1988
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.75
Pain Relevance 0.76

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small molecule metabolic process (GGT2) plasma membrane (GGT2) transferase activity, transferring acyl groups (GGT2)
cellular_component (GGT2)
Anatomy Link Frequency
urine 2
liver 1
GGT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 2 98.18 Very High Very High Very High
isoflurane 5 97.60 Very High Very High Very High
ketamine 2 95.40 Very High Very High Very High
Chronic pancreatitis 2 92.16 High High
headache 1 87.68 High High
anesthesia 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 6 100.00 Very High Very High Very High
Diabetes Mellitus 26 99.78 Very High Very High Very High
Toxicity 2 97.12 Very High Very High Very High
Pancreatic Cancer 2 93.64 High High
Pressure Volume 2 Under Development 1 93.20 High High
Diarrhoea 1 92.56 High High
Hematemesis 1 92.12 High High
Vomiting 1 91.60 High High
Dyspnea 1 91.20 High High
Ataxia 2 88.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Earlier work describing increased biliary excretion of the acetaminophen-cysteine conjugate advanced the hypothesis that streptozotocin-induced diabetes increases gamma-glutamyltranspeptidase (GGT) expression in Sprague-Dawley rats.
Gene_expression (expression) of gamma-glutamyltranspeptidase associated with paracetamol and diabetes mellitus
1) Confidence 0.21 Published 1998 Journal J. Biochem. Mol. Toxicol. Section Abstract Doc Link 9580874 Disease Relevance 0.72 Pain Relevance 0.10
Streptozotocin-induced diabetes increases gamma-glutamyltranspeptidase activity but not expression in rat liver.
Gene_expression (expression) of gamma-glutamyltranspeptidase in liver associated with diabetes mellitus
2) Confidence 0.18 Published 1998 Journal J. Biochem. Mol. Toxicol. Section Title Doc Link 9580874 Disease Relevance 0.93 Pain Relevance 0.10
Three and six hours after intraperitoneal injection of TBE, intramuscular injection of ketamine/xylazine combination (K/X), intraperitoneal injection of pentobarbital (PB), and inhalation of isoflurane (IF), or intraperitoneal and intramuscular injection of control saline, mice were exsanguinated and serum was obtained for measurement of hepatic aspartate transaminase (AST), alanine transaminase (ALT) and gamma-glutamyltransferase (GGT).
Gene_expression (measurement) of gamma-glutamyltransferase associated with ketamine and isoflurane
3) Confidence 0.06 Published 2002 Journal Comp. Med. Section Abstract Doc Link 11900415 Disease Relevance 0.18 Pain Relevance 0.30
In order to investigate the role of renal factors in affecting trypsinogen 1 metabolism and excretion in chronic pancreatic disease, serum immunoreactive trypsin (IRT), urinary IRT, gamma-glutamyltransferase (GGT), alpha-glucosidase (AGL) and RNase outputs and the molecular size distribution of serum and urine IRT were studied in 8 control subjects, 18 cases with pancreatic cancer, and 23 cases with chronic pancreatitis.
Gene_expression (metabolism) of gamma-glutamyltransferase in urine associated with pancreatic cancer, pancreatitis and chronic pancreatitis
4) Confidence 0.03 Published 1988 Journal Pancreas Section Abstract Doc Link 3362841 Disease Relevance 0.42 Pain Relevance 0.09
In order to investigate the role of renal factors in affecting trypsinogen 1 metabolism and excretion in chronic pancreatic disease, serum immunoreactive trypsin (IRT), urinary IRT, gamma-glutamyltransferase (GGT), alpha-glucosidase (AGL) and RNase outputs and the molecular size distribution of serum and urine IRT were studied in 8 control subjects, 18 cases with pancreatic cancer, and 23 cases with chronic pancreatitis.
Gene_expression (disease) of gamma-glutamyltransferase in urine associated with pancreatic cancer, pancreatitis and chronic pancreatitis
5) Confidence 0.03 Published 1988 Journal Pancreas Section Abstract Doc Link 3362841 Disease Relevance 0.42 Pain Relevance 0.09
The aim of this study was to measure the serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and of gamma-glutamyltransferase (gamma-GT) of the last five years in 40 printer workers after the removal of IPA from the industry.
Gene_expression (levels) of gamma-glutamyltransferase
6) Confidence 0.01 Published 2007 Journal G Ital Med Lav Ergon Section Abstract Doc Link 18409681 Disease Relevance 1.08 Pain Relevance 0.09

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