INT36571

Context Info Confidence 0.04 First Reported 1988 Last Reported 1988 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.19 Pain Relevance 0.29

extracellular region (MDK, PRL) cell proliferation (PRL) cytosol (PRL) cell differentiation (MDK) signal transduction (MDK)

MDK (Homo sapiens) PRL (Homo sapiens)

Pain Link Frequency Relevance Heat Serotonin 3 99.32 headache 1 94.56 agonist 2 75.00

Disease Link Frequency Relevance Heat Vomiting 1 95.00 Headache 1 94.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

MK-212 may stimulate the secretion of cortisol and prolactin in humans via a serotonin (5-HT2) receptor mechanism and may be a valuable tool with which to study 5-HT receptor sensitivity in humans.

MK-212 Spec (may) Positive_regulation (stimulate) of Localization (secretion) of prolactin associated with serotonin

1) Confidence 0.04 Published 1988 Journal Biol. Psychiatry Section Abstract Doc Link 3365458 Disease Relevance 0.19 Pain Relevance 0.29

General Comments

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