INT36594

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Context Info
Confidence 0.09
First Reported 1988
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.29
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (C4a) extracellular region (C4a) molecular_function (C4a)
Anatomy Link Frequency
joint 1
blood 1
C4a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 9 96.68 Very High Very High Very High
spinal inflammation 2 50.00 Quite Low
rheumatoid arthritis 2 50.00 Quite Low
Facet joint 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Sciatica 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 99 98.00 Very High Very High Very High
Osteoarthritis 53 97.86 Very High Very High Very High
Hyperplasia 100 97.12 Very High Very High Very High
Pain 3 96.68 Very High Very High Very High
Arthralgia 2 96.32 Very High Very High Very High
Low Back Pain 2 92.80 High High
Rheumatoid Arthritis 3 91.68 High High
Hemorrhage 1 89.88 High High
Systemic Lupus Erythematosus 25 50.00 Quite Low
Arthropathy 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lod scores showed no close genetic linkage of Factor XI:C deficiency with blood group MNSs (chromosome 4), complement components Bf and C4B (chromosome 6), or blood group P.
C4B Neg (no) Binding (linkage) of in blood
1) Confidence 0.09 Published 1988 Journal Am. J. Hematol. Section Abstract Doc Link 3369441 Disease Relevance 0.38 Pain Relevance 0.29
Only increasing ESR and low C4 level remained significantly associated with overall BILAG-2004 scores reflecting higher disease activity.


C4 Binding (associated) of associated with disease
2) Confidence 0.04 Published 2007 Journal Arthritis and Rheumatism Section Body Doc Link PMC2659367 Disease Relevance 0.50 Pain Relevance 0
METHODS: We tested the serum of patients for antinuclear antibodies (ANA), anti-DNA antibodies and C4 complement at baseline, and for each infusion for infliximab, and at month 3, 6 and 12 for etanercept.
C4 Binding (complement) of
3) Confidence 0.03 Published 2008 Journal Clin. Exp. Rheumatol. Section Body Doc Link 18578960 Disease Relevance 0.28 Pain Relevance 0
The C-coefficients and ORs for the segmental relationships between cervical pillar hyperplasia (CPH) and degenerative joint disease (DJD) across all age groups (40–69 years) indicate that the strongest associations of statistical significance occurred at C4 and C5; however, these correlation coefficients and ORs were all considerably weaker than the initially proposed clinically important 'moderate' associations represented by C ?
C4 Binding (occurred) of in joint associated with osteoarthritis and hyperplasia
4) Confidence 0.02 Published 2006 Journal Chiropr Osteopat Section Body Doc Link PMC1592100 Disease Relevance 1.13 Pain Relevance 0

General Comments

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