INT36619

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Context Info
Confidence 0.44
First Reported 1988
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 4.83
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SOCS1) cytoplasmic membrane-bounded vesicle (SOCS1) nucleus (SOCS1)
cytoplasm (SOCS1)
Anatomy Link Frequency
T cells 1
SOCS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 6 88.32 High High
Osteoarthritis 27 84.44 Quite High
depression 85 74.72 Quite High
rheumatoid arthritis 69 62.64 Quite High
COX2 1 58.32 Quite High
Pain 35 54.24 Quite High
metalloproteinase 1 48.24 Quite Low
antidepressant 26 41.76 Quite Low
Inflammation 12 39.56 Quite Low
anesthesia 2 9.88 Low Low
Disease Link Frequency Relevance Heat
Infection 14 100.00 Very High Very High Very High
Cancer 73 99.04 Very High Very High Very High
Dislocations 8 98.80 Very High Very High Very High
Adverse Drug Reaction 5 96.92 Very High Very High Very High
Epstein-barr Virus 44 96.40 Very High Very High Very High
Colorectal Cancer 50 95.92 Very High Very High Very High
Oliguria 9 95.12 Very High Very High Very High
Suicidal Behaviour 138 94.92 High High
Nasopharynx Cancer 145 93.76 High High
Carcinoma 18 85.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The synthesis of cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indole -1-acetic acid, pemedolac (USAN), is described.
Gene_expression (synthesis) of cis-1-ethyl-1
1) Confidence 0.44 Published 1988 Journal J. Med. Chem. Section Abstract Doc Link 3373493 Disease Relevance 0 Pain Relevance 0.16
They found that they could reliably identify tumours with the CIMP+ phenotype using a five gene set consisting of CACNA1G, IGF2, NEUROG1, RUNX3 and SOCS1, known collectively as the “CIMP Panel”
Gene_expression (consisting) of SOCS1 associated with cancer
2) Confidence 0.38 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 0.74 Pain Relevance 0.03
In the current series, the expression level of SOCS1 in expanded IL-17 producing T cells was significantly higher than in non-expanded cells.
Gene_expression (expression) of SOCS1 in T cells
3) Confidence 0.37 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2950393 Disease Relevance 0.29 Pain Relevance 0.09
We categorized total SSI scores as minimal (= ?
Gene_expression (scores) of SSI
4) Confidence 0.32 Published 2005 Journal BMC Psychiatry Section Body Doc Link PMC1183226 Disease Relevance 0.07 Pain Relevance 0.09
Increased expression of their downstream targets (c-Myc, bcl-xL, IL-6, LIF, SOCS-1, SOCS-3, VEGF and COX-2) was also observed.
Gene_expression (expression) of SOCS-1
5) Confidence 0.32 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1774581 Disease Relevance 1.92 Pain Relevance 0
VTE and SSI occurred in 8 patients (3%) each.
Gene_expression (occurred) of SSI associated with infection
6) Confidence 0.24 Published 2009 Journal Patient Saf Surg Section Body Doc Link PMC2674031 Disease Relevance 0.55 Pain Relevance 0.08
Both the scores on the SSI and item 18 of the IDS-SR were not normally distributed, because the majority of participants was non-suicidal (SSI: Skewness?
Neg (not) Gene_expression (distributed) of SSI
7) Confidence 0.15 Published 2009 Journal J Psychopathol Behav Assess Section Body Doc Link PMC2914256 Disease Relevance 0.44 Pain Relevance 0.04
Both the scores on the SSI and item 18 of the IDS-SR were not normally distributed, because the majority of participants was non-suicidal (SSI: Skewness?
Gene_expression (scores) of SSI
8) Confidence 0.15 Published 2009 Journal J Psychopathol Behav Assess Section Body Doc Link PMC2914256 Disease Relevance 0.47 Pain Relevance 0.03
Because the skewness of the SSI tends to be very high, it was decided only to include the first five items as part of the NESDA interview.
Gene_expression (skewness) of SSI
9) Confidence 0.15 Published 2009 Journal J Psychopathol Behav Assess Section Body Doc Link PMC2914256 Disease Relevance 0.36 Pain Relevance 0.03

General Comments

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