INT36684

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Context Info
Confidence 0.18
First Reported 1988
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Gh1, Prl) cytosol (Gh1) signal transduction (Gh1)
mitochondrion (Gh1) extracellular space (Gh1) plasma membrane (Gh1)
Gh1 (Rattus norvegicus)
Prl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 11 100.00 Very High Very High Very High
Dopamine 35 5.00 Very Low Very Low Very Low
gABA 16 5.00 Very Low Very Low Very Low
Locus ceruleus 10 5.00 Very Low Very Low Very Low
midbrain 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Somatostatin 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
nMDA receptor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 44 99.96 Very High Very High Very High
Schizophrenia 220 97.84 Very High Very High Very High
Disease 26 71.88 Quite High
Stress 14 68.56 Quite High
Communicable Diseases 2 62.20 Quite High
Hypospadias 3 18.96 Low Low
Stress Incontinence 1 15.20 Low Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 10 5.00 Very Low Very Low Very Low
Autism 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of morphine on circulating levels of prolactin and growth hormone (GH) in the lactating female model was determined at various time intervals following the termination of suckling.
GH Regulation (effect) of prolactin associated with morphine
1) Confidence 0.18 Published 1988 Journal Life Sci. Section Abstract Doc Link 3386414 Disease Relevance 0 Pain Relevance 0.48
Endocrine and neuroendocrine abnormalities in schizophrenia have been extensively described in the past.1,2 These abnormalities have included impaired growth hormone (GH) regulation, prolactin abnormalities especially related to antipsychotic medications, various changes in adrenocorticotropic hormone and cortisol, effects on vasopressin and oxytocin, and possible neuroprotective roles of estrogen and progesterone (PG).1 Many of these studies have concentrated on the neuroendocrine status of adults with schizophrenia.
GH Regulation (regulation) of prolactin associated with congenital anomalies and schizophrenia
2) Confidence 0.00 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 1.25 Pain Relevance 0

General Comments

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