INT36686

Context Info Confidence 0.19 First Reported 1988 Last Reported 2011 Negated 0 Speculated 0 Reported most in Body Documents 7 Total Number 7 Disease Relevance 3.12 Pain Relevance 0.45

extracellular space (Tg) extracellular region (Tg) Golgi apparatus (Tg) endoplasmic reticulum (Tg)

Anatomy Link Frequency thyroid 2 brain 1 Tg (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 61 88.20 antagonist 13 81.52 anesthesia 2 81.48 Inflammation 47 67.72 Lamotrigine 1 54.52 sodium channel 1 53.84 Transcranial magnetic stimulation 26 50.00 nMDA receptor 8 5.00 rheumatoid arthritis 5 5.00 Chronic pancreatitis 4 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 111 98.68 Nodular Goiter 2 96.84 Disorders Of The Lacrimal System 29 87.52 Alzheimer's Dementia 8 87.44 Stroke 66 85.68 Apoptosis 9 83.48 Hypothyroidism 16 71.16 INFLAMMATION 54 67.72 Thyroid Neoplasm 7 65.36 Hashimoto Disease 15 64.60

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Sequential changes in serum thyroglobulin, triiodothyronine, and thyroxine following partial thyroidectomy for nontoxic nodular goiter.

Regulation (changes) of thyroglobulin associated with nodular goiter

1) Confidence 0.19 Published 1988 Journal Metab. Clin. Exp. Section Title Doc Link 3386534 Disease Relevance 0.18 Pain Relevance 0.08

gene under control of the rat thyroglobulin promoter, to support transcription specifically in thyroid follicular cells.

Regulation (control) of thyroglobulin in thyroid

2) Confidence 0.19 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773418 Disease Relevance 1.35 Pain Relevance 0.03

Large intersession variation in either of these values will affect the COG value and subsequent calculation of displacement between sessions.

Regulation (affect) of COG

3) Confidence 0.08 Published 2005 Journal J Neuroengineering Rehabil Section Body Doc Link PMC1175099 Disease Relevance 0.17 Pain Relevance 0

Likewise, our standard deviation in COG values was very small, with a mean value of 1.1 mm in latitude and 1.3 mm in longitude across subjects.

Regulation (values) of COG

4) Confidence 0.05 Published 2005 Journal J Neuroengineering Rehabil Section Body Doc Link PMC1175099 Disease Relevance 0.22 Pain Relevance 0

Such an effect of memantine alone on the COG could additionally be excluded by comparing the baseline maps obtained prior to the motor learning with placebo and memantine in the ascending dosage experiment, which did not significantly differ from each other.

Regulation (effect) of COG

5) Confidence 0.02 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1134663 Disease Relevance 0 Pain Relevance 0.09

IL-12 SJL transgenic mice were made by expressing IL-12 p70 under the transcriptional control of the thyroglobulin promoter, resulting in IL-12 overexpression in the thyroid organ [69].

Regulation (control) of thyroglobulin promoter in thyroid associated with targeted disruption

6) Confidence 0.01 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018660 Disease Relevance 0.76 Pain Relevance 0.07

revealed a wide range of values across the TgAPPsw and PS1/APPsw mouse brain slices, with a 15.3-fold variance for A?

Regulation (values) of TgAPPsw in brain

7) Confidence 0.00 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC555557 Disease Relevance 0.45 Pain Relevance 0.17

General Comments

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