INT36779

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Context Info
Confidence 0.59
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.57
Pain Relevance 2.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HBG2) transport (HBG2)
Anatomy Link Frequency
upper limb 1
HBG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Regional anesthesia 6 100.00 Very High Very High Very High
anesthesia 47 99.14 Very High Very High Very High
lidocaine 7 98.66 Very High Very High Very High
local anesthetic 20 93.64 High High
nerve block 5 82.84 Quite High
analgesia 4 78.20 Quite High
Pain 35 71.64 Quite High
Analgesic 21 53.56 Quite High
ketamine 22 45.52 Quite Low
unmyelinated 1 9.52 Low Low
Disease Link Frequency Relevance Heat
Stress 1 95.80 Very High Very High Very High
Methemoglobinemia 26 88.88 High High
Cyanosis 12 85.60 High High
Dyspnea 2 84.64 Quite High
Hypesthesia 3 82.24 Quite High
Hypoxia 2 80.40 Quite High
Tinnitus 2 80.08 Quite High
Heart Rate Under Development 2 79.64 Quite High
Vomiting 1 78.96 Quite High
Pain 36 71.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under physiological conditions, there is a slow, constant loss of electrons to release oxygen and the ferric (Fe3+) form combines with water, producing methemoglobin.
Localization (release) of methemoglobin
1) Confidence 0.59 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2829598 Disease Relevance 0.54 Pain Relevance 0.81
In their study comparing the use of lidocaine and prilocaine for RIVA, Bader et al. determined that the highest methemoglobin levels occurred 60 minutes after the release of the tourniquet.
Localization (release) of methemoglobin associated with anesthesia and lidocaine
2) Confidence 0.40 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2954732 Disease Relevance 0.85 Pain Relevance 0.65
In order to study prilocaine mobilization after tourniquet release in the upper limb following IVRA, prilocaine and methemoglobin concentrations were measured in 8 patients.
Localization (release) of methemoglobin in upper limb associated with regional anesthesia
3) Confidence 0.37 Published 1988 Journal Reg Anaesth Section Abstract Doc Link 3406467 Disease Relevance 0.17 Pain Relevance 0.54

General Comments

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