INT36780

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Context Info
Confidence 0.34
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.28
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 4
Mln (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spastic colon 15 99.56 Very High Very High Very High
abdominal pain 1 92.32 High High
imagery 1 87.92 High High
Paracetamol 2 85.20 High High
Pain 1 80.96 Quite High
nud 1 80.60 Quite High
Neuropeptide 4 80.52 Quite High
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

11 99.56 Very High Very High Very High
Systemic Sclerosis 8 97.36 Very High Very High Very High
Diarrhoea 1 95.56 Very High Very High Very High
Syndrome 1 91.36 High High
Arrhythmia Under Development 3 83.76 Quite High
Functional Bowel Disorder 4 83.20 Quite High
Pain 1 80.96 Quite High
Dyspepsia 1 80.60 Quite High
Vomiting 1 79.80 Quite High
Abdominal Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In IBS patients circulating motilin levels covaried with total ghrelin levels (r=0.90; p<0.004), octanylated ghrelin (r=0.77; p<0.02) and desoctanylated ghrelin (r=0.69; p<0.04).
Negative_regulation (octanylated) of Gene_expression (levels) of motilin associated with spastic colon
1) Confidence 0.34 Published 2010 Journal Peptides Section Abstract Doc Link 20338210 Disease Relevance 0.16 Pain Relevance 0.65
Correlations are also noted between plasma VIP/Motilin levels and gastric slow waves.
Negative_regulation (noted) of Gene_expression (levels) of Motilin in plasma
2) Confidence 0.20 Published 2009 Journal Neurogastroenterol. Motil. Section Abstract Doc Link 19566588 Disease Relevance 0.97 Pain Relevance 0.12
In constipated patients fasting levels of gastrin and motilin and postprandial levels of gastrin, motilin and PP were decreased.
Negative_regulation (decreased) of Gene_expression (levels) of motilin
3) Confidence 0.19 Published 1987 Journal Scand. J. Gastroenterol. Suppl. Section Abstract Doc Link 3477012 Disease Relevance 0.33 Pain Relevance 0.72
Post-prandial plasma motilin levels were significantly depressed by IV glucose.
Negative_regulation (depressed) of Gene_expression (levels) of motilin in plasma
4) Confidence 0.03 Published 1988 Journal Br. J. Nutr. Section Abstract Doc Link 3408703 Disease Relevance 0 Pain Relevance 0.20

General Comments

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