INT36854

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Context Info
Confidence 0.15
First Reported 1988
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.32
Pain Relevance 1.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (P2RY6) signal transducer activity (P2RY6)
Anatomy Link Frequency
internal anal sphincter 2
P2RY6 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 18 100.00 Very High Very High Very High
agonist 24 96.76 Very High Very High Very High
adenocard 11 95.64 Very High Very High Very High
chemokine 4 91.28 High High
cytokine 68 90.24 High High
Inflammation 19 81.92 Quite High
tetrodotoxin 2 80.56 Quite High
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 2 82.36 Quite High
Pneumonia 1 81.92 Quite High
Infection 1 77.12 Quite High
Injury 1 76.44 Quite High
INFLAMMATION 19 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 6 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, human promonocytic U937 cells stably transfected with human P2Y6 receptor secrete IL-8 when stimulated with UDP [45].
P2Y6 Binding (receptor) of
1) Confidence 0.15 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2096759 Disease Relevance 0.32 Pain Relevance 0.33
The inhibitory response to adenosine (P1 purinoceptor agonist), ATP (P2 purinoceptor agonist), RD, and SNS on the internal anal sphincter (IAS) was examined before and after 8-phenyltheophylline (P1 purinoceptor antagonist) and alpha,beta-methylene ATP (P2 purinoceptor antagonist that irreversibly binds and desensitizes P2 purinoceptor).
P2 purinoceptor Binding (binds) of in internal anal sphincter associated with adenocard, antagonist and agonist
2) Confidence 0.12 Published 1988 Journal Am. J. Physiol. Section Abstract Doc Link 3421341 Disease Relevance 0 Pain Relevance 0.72
The inhibitory response to adenosine (P1 purinoceptor agonist), ATP (P2 purinoceptor agonist), RD, and SNS on the internal anal sphincter (IAS) was examined before and after 8-phenyltheophylline (P1 purinoceptor antagonist) and alpha,beta-methylene ATP (P2 purinoceptor antagonist that irreversibly binds and desensitizes P2 purinoceptor).
P2 purinoceptor Binding (binds) of in internal anal sphincter associated with adenocard, antagonist and agonist
3) Confidence 0.12 Published 1988 Journal Am. J. Physiol. Section Abstract Doc Link 3421341 Disease Relevance 0 Pain Relevance 0.72

General Comments

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