INT36880

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Context Info
Confidence 0.37
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 1.37
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PRB1) molecular_function (PRB1) biological_process (PRB1)
Anatomy Link Frequency
joint 1
PRB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 38 100.00 Very High Very High Very High
Catecholamine 2 94.40 High High
Clonidine 2 83.76 Quite High
depression 4 50.00 Quite Low
imagery 28 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Premenstrual Syndrome 67 100.00 Very High Very High Very High
Cancer 45 99.28 Very High Very High Very High
Disease 24 97.60 Very High Very High Very High
Stress 2 95.28 Very High Very High Very High
Ovarian Cancer 14 94.48 High High
Bradycardia 2 90.04 High High
Breast Cancer 90 56.80 Quite High
Depression 4 50.00 Quite Low
Metastasis 11 37.60 Quite Low
Cognitive Disorder 2 33.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the PMS group, however, Total power and HF power were significantly decreased in the late luteal phase from the follicular phase.
Negative_regulation (decreased) of PMS associated with dismenorea
1) Confidence 0.37 Published 2007 Journal Biopsychosoc Med Section Body Doc Link PMC2253548 Disease Relevance 0.27 Pain Relevance 0.17
Detailed output of human SEC61B hybridization to 203133_at probe set (Figures 1A and 2A) shows that signal intensity value of PM (perfect match or total signal) obtained for 11th probe pair is higher than that of MM (mismatch or background signal).
Negative_regulation (value) of PM
2) Confidence 0.25 Published 2005 Journal BMC Genomics Section Body Doc Link PMC1156887 Disease Relevance 0 Pain Relevance 0
We found that masking of probes which poorly performed (PM-MM?
Negative_regulation (performed) of PM
3) Confidence 0.25 Published 2005 Journal BMC Genomics Section Body Doc Link PMC1156887 Disease Relevance 0 Pain Relevance 0
Functional inactivation of pRB1 in various human cancers leads to deregulated E2F1 activity [46].
Negative_regulation (inactivation) of pRB1 associated with cancer
4) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955548 Disease Relevance 0.50 Pain Relevance 0
Stimulation of AC through Ns-protein is potentiated by EtOH, but inhibition of AC through the Ni-protein is little affected by EtOH.
Negative_regulation (inhibition) of Ni-protein
5) Confidence 0.06 Published 1987 Journal Alcohol Alcohol Suppl Section Abstract Doc Link 3426758 Disease Relevance 0 Pain Relevance 0.21
In fact, what at first appeared to be a J-shaped relationship in the independent model (model 1) became an approximately linear relationship when the joint effect of PM10 and temperature was taken into account (model 2).
Negative_regulation (effect) of PM10 in joint
6) Confidence 0.02 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1665419 Disease Relevance 0 Pain Relevance 0
Therefore, both high ambient temperature and high ambient PM10 may interact to synergistically effect human morbidity/mortality.
Negative_regulation (effect) of PM10
7) Confidence 0.02 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1665419 Disease Relevance 0.35 Pain Relevance 0
As of 2002, more mutation carriers have undergone a PM, although the number of PMs in 2004 again was not different between mutation and 50% risk carriers.


Negative_regulation (number) of PMs
8) Confidence 0.01 Published 2007 Journal Ann Surg Oncol Section Body Doc Link PMC2077910 Disease Relevance 0.05 Pain Relevance 0
In Fig. 1, the number of PMs per year, separately for unaffected/affected BRCA mutation carriers, as well as for unaffected/affected 50% risk carriers is shown.
Negative_regulation (number) of PMs
9) Confidence 0.01 Published 2007 Journal Ann Surg Oncol Section Body Doc Link PMC2077910 Disease Relevance 0.21 Pain Relevance 0

General Comments

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