INT36886

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Context Info
Confidence 0.69
First Reported 1987
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 6
Total Number 7
Disease Relevance 3.16
Pain Relevance 2.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Myc) DNA binding (Myc) protein complex (Myc)
cytoplasm (Myc) pigmentation (Myc) chromosome organization (Myc)
Anatomy Link Frequency
RMIC 1
hilus 1
endometrium 1
Myc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
endometriosis 46 99.76 Very High Very High Very High
qutenza 14 99.72 Very High Very High Very High
Morphine 13 99.60 Very High Very High Very High
nalbuphine 1 98.48 Very High Very High Very High
anticonvulsant 1 95.92 Very High Very High Very High
anesthesia 4 94.96 High High
Neuropeptide 4 94.32 High High
Opioid 1 88.88 High High
Hippocampus 4 88.00 High High
Enkephalin 1 74.00 Quite High
Disease Link Frequency Relevance Heat
Endometriosis 48 99.76 Very High Very High Very High
Cancer 13 99.24 Very High Very High Very High
Stomach Cancer 3 94.16 High High
Convulsion 5 92.00 High High
Injury 132 80.48 Quite High
Renal Disease 1 80.44 Quite High
Death 10 79.68 Quite High
Apoptosis 41 78.96 Quite High
Keloid Scars 1 78.16 Quite High
Lung Cancer 1 77.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine also enhanced mRNA expression for c-jun and c-myc on RMIC.
Transcription (expression) of c-myc in RMIC associated with morphine
1) Confidence 0.69 Published 1997 Journal Nephron Section Abstract Doc Link 9346391 Disease Relevance 0.16 Pain Relevance 1.11
It was found that CAP enhanced the transcripts of two proto-oncogenes (c-myc and c-Ha-ras) and tumor suppressor gene p53.
Transcription (transcripts) of c-myc associated with qutenza and cancer
2) Confidence 0.69 Published 1997 Journal Cancer Lett. Section Abstract Doc Link 9461043 Disease Relevance 0.97 Pain Relevance 0.94
ODC inactivation is associated with decreased transcription of the growth-related c-myc and c-fos genes.
Transcription (transcription) of c-myc
3) Confidence 0.69 Published 2007 Journal Biochem. Soc. Trans. Section Abstract Doc Link 17371277 Disease Relevance 0.45 Pain Relevance 0
Messenger RNA for c-H-ras was not altered at any time following the lesion and c-myc mRNA was not reliably detected in either control or hilus lesioned rats.
Neg (not) Transcription (detected) of c-myc in hilus
4) Confidence 0.67 Published 1987 Journal Brain Res. Section Abstract Doc Link 3427445 Disease Relevance 0.40 Pain Relevance 0.55
The abundance of c-myc mRNA was not significantly changed throughout the menstrual cycle in both types of endometrium; however, the proto-oncogen was 65% higher in proliferative endometrium with endometriosis than normal endometrium, respectively (p < 0.05) (Figure 2).


Transcription (abundance) of c-myc in endometrium associated with endometriosis
5) Confidence 0.67 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1262771 Disease Relevance 0.67 Pain Relevance 0.26
Cluster profile 5 on the other hand contains two differentially expressed genes coding for transcription factors, MYC (Myc) and ATF3 (Atf3).
Transcription (transcription) of Myc
6) Confidence 0.61 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2900267 Disease Relevance 0.26 Pain Relevance 0
Cluster profile 5 on the other hand contains two differentially expressed genes coding for transcription factors, MYC (Myc) and ATF3 (Atf3).
Transcription (transcription) of MYC
7) Confidence 0.61 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2900267 Disease Relevance 0.25 Pain Relevance 0

General Comments

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