INT36926

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Context Info
Confidence 0.24
First Reported 1987
Last Reported 1995
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tac1) extracellular region (Tac1) plasma membrane (Tac1)
Anatomy Link Frequency
striatum 2
Tac1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dopamine receptor 2 100.00 Very High Very High Very High
Neuropeptide 4 75.00 Quite High
Neurotransmitter 2 75.00 Quite High
Dopamine 2 58.60 Quite High
Enkephalin 4 56.80 Quite High
Substantia nigra 1 41.72 Quite Low
cerebral cortex 1 40.36 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have investigated the effect of dopamine receptor blockade on striatal proenkephalin mRNA and protachykinin mRNA by Northern gel analysis and by in situ hybridization histochemistry.
Spec (investigated) Regulation (effect) of Spec (investigated) Negative_regulation (blockade) of protachykinin associated with dopamine receptor
1) Confidence 0.24 Published 1987 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 3434462 Disease Relevance 0 Pain Relevance 0.16
The cortical lesions had no significant effect on the 6-OHDA-induced reduction of PPT mRNA levels neither in the remaining lost striatum nor in the striatal graft.
Neg (no) Regulation (effect) of Negative_regulation (reduction) of PPT in striatum
2) Confidence 0.01 Published 1995 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 7609615 Disease Relevance 0 Pain Relevance 0.16

General Comments

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