INT36930

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Context Info
Confidence 0.22
First Reported 1987
Last Reported 1997
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.10
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
hearts 2
NA (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 23 100.00 Very High Very High Very High
lidocaine 21 99.36 Very High Very High Very High
antiarrhythmic agent 1 96.64 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 21 100.00 Very High Very High Very High
Coronary Artery Disease 2 99.64 Very High Very High Very High
Contracture 2 44.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of the Na+ channel in the accumulation of intracellular Na+ during myocardial ischemia: consequences for post-ischemic recovery.
Regulation (role) of Positive_regulation (accumulation) of Na associated with coronary artery disease and ischemia
1) Confidence 0.22 Published 1997 Journal J. Mol. Cell. Cardiol. Section Title Doc Link 9040024 Disease Relevance 0.44 Pain Relevance 0.70
To further elucidate the role of the Na+ channel in the ischemic accumulation of intracellular Na+ (Na+i), 200 microM lidocaine was included in the perfusate for 5 min prior to 30 min of ischemia in isolated rat hearts paced at 5 Hz.
Regulation (role) of Positive_regulation (accumulation) of Na in hearts associated with ischemia and lidocaine
2) Confidence 0.22 Published 1997 Journal J. Mol. Cell. Cardiol. Section Abstract Doc Link 9040024 Disease Relevance 0.23 Pain Relevance 0.34
Na+i concentration elevated by ischemia was not further affected by reperfusion.
Neg (not) Regulation (affected) of Positive_regulation (elevated) of Na associated with ischemia
3) Confidence 0.14 Published 1987 Journal Biomed. Biochim. Acta Section Abstract Doc Link 3435510 Disease Relevance 0.42 Pain Relevance 0.35

General Comments

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