INT36931

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Context Info
Confidence 0.24
First Reported 1987
Last Reported 2006
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.28
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Dao) peroxisome (Dao)
Anatomy Link Frequency
anterior 1
DAO 1
Dao (Rattus norvegicus)
Pain Link Frequency Relevance Heat
projection neuron 5 99.96 Very High Very High Very High
Anterior cingulate cortex 2 99.36 Very High Very High Very High
antagonist 1 96.72 Very High Very High Very High
nMDA receptor 6 95.36 Very High Very High Very High
Pain 7 94.60 High High
Glutamate 1 87.08 High High
nociceptor 2 76.64 Quite High
Dorsal column 1 56.20 Quite High
Lasting pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 5 94.60 High High
Nociception 1 57.60 Quite High
Shock 1 54.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using a combination of a rat formalin-induced conditioned place avoidance (F-CPA) behavioral model and whole-cell patch-clamp recording in rostral anterior cingulate cortex (rACC) slices, we examined the effects of d-amino acid oxidase (DAAO), an endogenous D-serine-degrading enzyme, and 7-chlorokynurenate (7Cl-KYNA), an antagonist of the glycine site of NMDA receptors, on pain-related aversion.
Spec (examined) Regulation (effects) of DAAO in anterior associated with pain, nmda receptor, antagonist and anterior cingulate cortex
1) Confidence 0.24 Published 2006 Journal J. Neurochem. Section Abstract Doc Link 16476080 Disease Relevance 0.28 Pain Relevance 0.53
The limited responsiveness of the DAO projection neurons is, however, not uncharacteristic of DCN but places this projection at one end of the spectrum of DCN efferents, with the diencephalic projection at the other end.
Regulation (responsiveness) of DAO in DAO associated with projection neuron
2) Confidence 0.16 Published 1987 Journal Exp Brain Res Section Abstract Doc Link 3436383 Disease Relevance 0 Pain Relevance 0.31

General Comments

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