INT37006

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Context Info
Confidence 0.13
First Reported 1986
Last Reported 2002
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.74
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (S100a4)
Anatomy Link Frequency
Plasma 1
S100a4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 26 100.00 Very High Very High Very High
tolerance 6 97.28 Very High Very High Very High
cytokine 2 95.08 Very High Very High Very High
anesthesia 2 84.08 Quite High
Inflammation 1 66.40 Quite High
antiepileptic Drug 1 55.28 Quite High
cINOD 2 28.80 Quite Low
Disease Link Frequency Relevance Heat
Hemorrhage 26 100.00 Very High Very High Very High
Sepsis 2 95.00 High High
Convulsion 1 68.08 Quite High
INFLAMMATION 3 66.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of tolerizing sublethal hemorrhage on p44/42 and SAPK/JNK Map-kinase activation.
Regulation (Effects) of p44/42 associated with cva
1) Confidence 0.13 Published 2002 Journal Shock Section Title Doc Link 12166775 Disease Relevance 0.92 Pain Relevance 0.63
The purpose of this study was to explore whether changes in p44/42 and SAPK/JNK MAP kinase activity also occur after the induction of tolerance by SLH.
Spec (whether) Regulation (changes) of p44/42 associated with tolerance and cva
2) Confidence 0.08 Published 2002 Journal Shock Section Abstract Doc Link 12166775 Disease Relevance 0.68 Pain Relevance 0.52
Plasma protein binding of I having pKa value of 8.30 was about 88%, whereas that of II having pKa value of 4.89 was about 99%.
Regulation (value) of pKa in Plasma
3) Confidence 0.03 Published 1986 Journal J. Pharmacobio-dyn. Section Abstract Doc Link 3459864 Disease Relevance 0.13 Pain Relevance 0.06

General Comments

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