INT37132

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Context Info
Confidence 0.36
First Reported 1986
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.42
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (SERPINF1) extracellular space (SERPINF1) aging (SERPINF1)
extracellular region (SERPINF1)
Anatomy Link Frequency
endothelium 2
abdominal aorta 2
SERPINF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 6 99.38 Very High Very High Very High
adenocard 1 80.68 Quite High
Clonidine 2 72.04 Quite High
Serotonin 1 64.64 Quite High
Disease Link Frequency Relevance Heat
Hyperlipidemia 5 97.44 Very High Very High Very High
Hypertension 2 75.00 Quite High
Stroke 1 55.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The acetylcholine-induced release of endothelium-derived relaxant factor from the abdominal aorta was not significantly affected by the hypercholesterolemia.
Positive_regulation (induced) of Localization (release) of endothelium-derived relaxant factor in abdominal aorta associated with hyperlipidemia
1) Confidence 0.36 Published 1986 Journal Circ. Res. Section Abstract Doc Link 3486053 Disease Relevance 0.24 Pain Relevance 0.14
These results suggest that the impairment of relaxation by alpha(2)-agonists in SHRSP is not caused by the increase in the release of endothelium-derived contracting factor (EDCF) but by the reduction in the release of nitric oxide (NO).
Positive_regulation (increase) of Localization (release) of endothelium-derived contracting factor in endothelium associated with agonist
2) Confidence 0.00 Published 1996 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 8859945 Disease Relevance 0.19 Pain Relevance 0.32

General Comments

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