INT37153

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Context Info
Confidence 0.12
First Reported 1986
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptpn2) endoplasmic reticulum (Ptpn2) nucleus (Ptpn2)
cytoplasm (Ptpn2)
Mpz (Mus musculus)
Ptpn2 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 12 99.92 Very High Very High Very High
Potency 4 98.48 Very High Very High Very High
Catecholamine 1 93.20 High High
Analgesic 4 81.84 Quite High
monoamine 2 75.00 Quite High
cerebral cortex 1 71.00 Quite High
5HT 1 68.32 Quite High
Serotonin 1 68.12 Quite High
Disease Link Frequency Relevance Heat
Parkinson's Disease 8 100.00 Very High Very High Very High
Disease 1 57.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MPP+ was also more potent than MPTP in releasing endogenous DA from striatal synaptosomes (EC50 = 3 vs. 30 microM), but did not release the cytoplasmic markers tyrosine hydroxylase and lactate dehydrogenase (LDH).
MPP Binding (potent) of MPTP associated with parkinson's disease and dopamine
1) Confidence 0.12 Published 1986 Journal Life Sci. Section Abstract Doc Link 3490612 Disease Relevance 0.68 Pain Relevance 1.08

General Comments

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