INT37170

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Context Info
Confidence 0.36
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 4.79
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (APCS) protein folding (APCS) extracellular space (APCS)
extracellular region (APCS) protein complex (APCS)
Anatomy Link Frequency
cheek 1
SVR 1
T-cell 1
APCS (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 92 99.88 Very High Very High Very High
Inflammation 71 96.08 Very High Very High Very High
chemokine 18 91.36 High High
depression 1 88.72 High High
anesthesia 5 85.92 High High
nud 1 70.64 Quite High
alcohol 5 66.16 Quite High
Morphine 1 51.80 Quite High
Bile 1 43.84 Quite Low
cytokine 23 38.80 Quite Low
Disease Link Frequency Relevance Heat
Pancreatitis 14 100.00 Very High Very High Very High
Mucositis 129 99.88 Very High Very High Very High
Fibrosis 125 99.88 Very High Very High Very High
Compartment Syndromes 17 99.72 Very High Very High Very High
Ventral Hernia 5 98.12 Very High Very High Very High
INFLAMMATION 79 96.08 Very High Very High Very High
Apoptosis 25 88.76 High High
Respiratory Failure 1 88.72 High High
Infection 37 88.08 High High
Impotence 1 84.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All data were expressed as a ratio of ICP:SAP.
SAP Binding (ratio) of
1) Confidence 0.36 Published 2002 Journal J. Androl. Section Abstract Doc Link 12002434 Disease Relevance 0.24 Pain Relevance 0
Decreasing arterial PCO2 to the awake value by controlled ventilation increased SVR (P less than 0.05), but the associated increased SAP and decreased Q70 did not reach statistical significance.
SAP Binding (associated) of in SVR
2) Confidence 0.35 Published 1987 Journal Anesth. Analg. Section Abstract Doc Link 3492156 Disease Relevance 0.09 Pain Relevance 0.31
Acute dosing with SAP at the time of radiation gives greatest protection
SAP Binding (dosing) of
3) Confidence 0.23 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2905325 Disease Relevance 0.73 Pain Relevance 0.12
SAP inhibits radiation-induced mucositis
SAP Binding (radiation) of associated with mucositis
4) Confidence 0.20 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2905325 Disease Relevance 1.19 Pain Relevance 0.17
SAP inhibits radiation-induced fibrosis in the hamster cheek pouch
SAP Binding (radiation) of in cheek associated with fibrosis
5) Confidence 0.20 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2905325 Disease Relevance 1.07 Pain Relevance 0.09
B7-H3 is a B7 homolog inducible in APCs, which binds a putative receptor on T-cells, resulting in increased T-cell proliferation.
APCs Binding (binds) of in T-cell
6) Confidence 0.15 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721321 Disease Relevance 0.07 Pain Relevance 0
We present a patient with SAP where ACS was treated with transverse subcostal decompressive laparostomy and subsequent gradual delayed primary closure of the abdominal wall.


SAP Binding (patient) of associated with compartment syndromes and pancreatitis
7) Confidence 0.13 Published 2008 Journal World J Emerg Surg Section Body Doc Link PMC2266717 Disease Relevance 1.04 Pain Relevance 0.09
The function of APCs is largely governed by their recruitment and relocation properties.
APCs Binding (recruitment) of
8) Confidence 0.11 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2637987 Disease Relevance 0.36 Pain Relevance 0.19

General Comments

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