INT37203

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Context Info
Confidence 0.06
First Reported 1987
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.64
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (Pygm) carbohydrate metabolic process (Pygm) cytoplasm (Pygm)
Pygm (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 52 99.66 Very High Very High Very High
Inflammation 13 94.48 High High
withdrawal 2 92.56 High High
Analgesic 4 89.72 High High
aspirin 1 88.04 High High
Arthritis 4 76.28 Quite High
bradykinin 1 60.84 Quite High
COX2 2 25.00 Low Low
Pain 24 5.00 Very Low Very Low Very Low
visual analogue scale 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 6 99.52 Very High Very High Very High
INFLAMMATION 20 94.48 High High
Syndrome 1 93.32 High High
Anaphylaxis 1 82.64 Quite High
Experimental Arthritis 1 76.28 Quite High
Granuloma 1 71.44 Quite High
Phosphate Metabolism Disorders 110 70.12 Quite High
Pressure And Volume Under Development 3 69.96 Quite High
Arthritis 3 67.92 Quite High
Pain 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The low ulcerogenic potential of these compounds in animal models may be related to their relative inability to inhibit PG synthetase.
Negative_regulation (inhibit) of PG synthetase
1) Confidence 0.06 Published 1987 Journal Arzneimittelforschung Section Abstract Doc Link 3496890 Disease Relevance 0.80 Pain Relevance 0.28
It reduces the levels of biologically active PGs and inhibits PG actions in PCa cells, thereby decreasing the proliferative stimulus of PGs.
Negative_regulation (inhibits) of PG associated with reprotox - general 1
2) Confidence 0.02 Published 2006 Journal Anticancer Res. Section Abstract Doc Link 16886660 Disease Relevance 0.41 Pain Relevance 0.16
This was consistent with a rise in PG levels before each treatment cycle.
Negative_regulation (rise) of PG
3) Confidence 0.01 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1533806 Disease Relevance 0.27 Pain Relevance 0.43
Previously, we have shown that one single 5-week long NSAID treatment cycle reduced PG levels in the patients studied [17].
Negative_regulation (reduced) of PG associated with cinod
4) Confidence 0.01 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1533806 Disease Relevance 0.15 Pain Relevance 0.47

General Comments

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