INT37220

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Context Info
Confidence 0.43
First Reported 1987
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.46
Pain Relevance 1.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TACR1) cytoplasm (TACR1) signal transducer activity (TACR1)
Anatomy Link Frequency
neurons 2
TACR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 21 100.00 Very High Very High Very High
Morphine 8 100.00 Very High Very High Very High
substance P 49 99.88 Very High Very High Very High
Opioid 2 96.92 Very High Very High Very High
opioid receptor 3 96.88 Very High Very High Very High
depression 1 94.88 High High
Central nervous system 1 92.84 High High
Neuropeptide 2 88.96 High High
agonist 8 88.44 High High
Potency 2 82.56 Quite High
Disease Link Frequency Relevance Heat
Stress 2 98.92 Very High Very High Very High
Anxiety Disorder 1 95.24 Very High Very High Very High
Depression 1 94.88 High High
Increased Venous Pressure Under Development 2 75.00 Quite High
Ganglion Cysts 1 25.00 Low Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Asthma 3 5.00 Very Low Very Low Very Low
Nicotine Addiction 3 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 2 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of tachykinin receptor antagonists on cumulative additions of hHK-1 to guinea pig airways
Regulation (Effects) of Gene_expression (antagonists) of tachykinin receptor associated with antagonist
1) Confidence 0.43 Published 2010 Journal Respir Res Section Body Doc Link PMC2959027 Disease Relevance 0 Pain Relevance 0.51
Thus, the differences in pharmacokinetical properties makes it difficult to draw major conclusions about tachykinin receptor subtypes based on biological potencies in vivo.
Regulation (about) of Gene_expression (subtypes) of tachykinin receptor
2) Confidence 0.11 Published 1987 Journal Acta Physiol Scand Suppl Section Abstract Doc Link 3499054 Disease Relevance 0.07 Pain Relevance 0.11
We examined the effects of morphine, the principal metabolite of heroin, on the functional expression of NK-1R in the cortical neurons.
Spec (examined) Regulation (effects) of Gene_expression (expression) of NK-1R in neurons associated with morphine
3) Confidence 0.07 Published 2006 Journal J. Neurosci. Res. Section Abstract Doc Link 16983662 Disease Relevance 0.38 Pain Relevance 1.11

General Comments

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