INT37289

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Context Info
Confidence 0.39
First Reported 1985
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.30
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GIP) small molecule metabolic process (GIP) extracellular region (GIP)
cytoplasm (GIP)
Anatomy Link Frequency
plasma 2
fat 1
gut 1
GIP (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 6 99.84 Very High Very High Very High
Paracetamol 3 80.48 Quite High
nud 1 35.44 Quite Low
antagonist 30 5.00 Very Low Very Low Very Low
agonist 14 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 5 93.12 High High
Disease 2 69.12 Quite High
Osteoporosis 1 54.88 Quite High
Diabetes Mellitus 2 41.84 Quite Low
Dyspepsia 1 35.44 Quite Low
Hyperinsulinism 1 25.00 Low Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Hyperglycemia 2 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated the role of glucose-dependent insulintropic polypeptide (GIP) in the regulation of gastric emptying (GE), appetite, energy intake (EI), energy expenditure (EE), plasma levels of triglycerides (TAG), and free fatty acids (FFA) in humans.
Regulation (regulation) of GIP in plasma
1) Confidence 0.39 Published 2010 Journal Am. J. Physiol. Endocrinol. Metab. Section Abstract Doc Link 19996386 Disease Relevance 0 Pain Relevance 0.07
Postprandial GIP secretion and plasma motilin levels were unaffected by addition of guar gum to the fat meal. 5 and 10 g guar gum/l solutions in water possessed buffering capacities between pH 2.75 and 5.5.
Neg (unaffected) Regulation (unaffected) of GIP in fat
2) Confidence 0.31 Published 1985 Journal Br. J. Nutr. Section Abstract Doc Link 4063284 Disease Relevance 0 Pain Relevance 0.08
The effect of guar gum on carbohydrate-, fat- and protein-stimulated gut hormone secretion: modification of postprandial gastric inhibitory polypeptide and gastrin responses.
Regulation (responses) of gastric inhibitory polypeptide in gut
3) Confidence 0.19 Published 1985 Journal Br. J. Nutr. Section Title Doc Link 4063284 Disease Relevance 0 Pain Relevance 0.08
When glucose was given intravenously, morphine had no effect on plasma glucose, insulin, glucose-dependent insulinotropic polypeptide (GIP), or pancreatic glucagon.
Neg (no) Regulation (effect) of insulinotropic in plasma associated with morphine
4) Confidence 0.07 Published 1986 Journal Diabetes Section Abstract Doc Link 3512343 Disease Relevance 0 Pain Relevance 0.50
Glucagon regulates hepatic glucose output [45, 52, 77], and post-prandial glucose homeostasis is modulated by the incretin peptides glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) [18, 52, 77].
Regulation (modulated) of glucose-dependent insulinotropic peptide
5) Confidence 0.01 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2656815 Disease Relevance 0.30 Pain Relevance 0

General Comments

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