INT37308

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Context Info
Confidence 0.20
First Reported 1986
Last Reported 1986
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ins1, Gast) signal transduction (Gast) extracellular space (Ins1)
carbohydrate metabolic process (Ins1) cytoplasm (Ins1)
Anatomy Link Frequency
stomach 2
Ins1 (Rattus norvegicus)
Gast (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 15 100.00 Very High Very High Very High
Somatostatin 3 98.80 Very High Very High Very High
Enkephalin 15 96.92 Very High Very High Very High
Neurotransmitter 12 94.00 High High
opiate 3 25.00 Low Low
antagonist 3 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since previous studies have shown that insulin, the major regulatory hormone of glucose metabolism, reduces gastric somatostatin and glucagon secretion it was of interest to determine the effect of insulin on gastric BLI and gastrin secretion.
insulin Spec (determine) Regulation (effect) of Localization (secretion) of gastrin associated with somatostatin
1) Confidence 0.20 Published 1986 Journal Neuropeptides Section Abstract Doc Link 3513044 Disease Relevance 0 Pain Relevance 0.32
The addition of porcine insulin to the perfusate at concentrations of 50 and 100 microU/ml had no effect on basal BLI and gastrin secretion.
insulin Neg (no) Regulation (effect) of Localization (secretion) of gastrin
2) Confidence 0.18 Published 1986 Journal Neuropeptides Section Abstract Doc Link 3513044 Disease Relevance 0 Pain Relevance 0.33
Effect of insulin on secretion of bombesin-like immunoreactivity and gastrin from the isolated rat stomach in response to acetylcholine, VIP and leucine-enkephalin.
insulin Regulation (Effect) of Localization (secretion) of gastrin in stomach associated with narcan and enkephalin
3) Confidence 0.12 Published 1986 Journal Neuropeptides Section Title Doc Link 3513044 Disease Relevance 0 Pain Relevance 0.31

General Comments

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