INT37381

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Context Info
Confidence 0.25
First Reported 1986
Last Reported 2009
Negated 3
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 0.73
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
reticulum 1
Sis (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 1 93.16 High High
Clonidine 3 75.00 Quite High
abdominal pain 1 73.60 Quite High
cINOD 5 58.48 Quite High
MU agonist 1 55.12 Quite High
corticosteroid 7 48.64 Quite Low
Pain 14 24.48 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shoulder Impingement Syndrome 26 100.00 Very High Very High Very High
Diabetes Mellitus 2 97.32 Very High Very High Very High
Impaired Glucose Tolerance 1 93.48 High High
Flatulence 1 74.08 Quite High
Abdominal Pain 1 73.60 Quite High
Diarrhoea 1 72.88 Quite High
Recurrence 9 40.64 Quite Low
Pain 11 24.48 Low Low
Rotator Cuff Tears 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The study is designed as a randomized controlled trial to evaluate the effectiveness of a new interdisciplinary treatment strategy for SIS.
Regulation (effectiveness) of SIS associated with shoulder impingement syndrome
1) Confidence 0.25 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1821022 Disease Relevance 0.32 Pain Relevance 0.06
The activities of neutral alpha-glucosidase (endoplasmic reticulum) or acid phosphatase and N-acetyl-beta-D-glucosaminidase (lysosomes) were not affected by mannoheptulose. 2-Deoxyglucose (5 mmol/l), another glucose analogue, did not increase insulin secretion or acid alpha-glucosidase activity at low glucose.
Neg (not) Regulation (affected) of alpha-glucosidase in reticulum
2) Confidence 0.05 Published 1993 Journal Pharmacology Section Abstract Doc Link 8441762 Disease Relevance 0 Pain Relevance 0.07
At high glucose, however, a partial inhibition of both insulin release (approximately 50%) and acid alpha-glucosidase activity was seen. 2-Deoxyglucose slightly suppressed acid phosphatase activity but did not influence the activities of neutral alpha-glucosidase or N-acetyl-beta-D- glucosaminidase.
Neg (not) Regulation (influence) of alpha-glucosidase
3) Confidence 0.05 Published 1993 Journal Pharmacology Section Abstract Doc Link 8441762 Disease Relevance 0 Pain Relevance 0.07
Loperamide inhibited intestinal Na+, K+-ATPase activity, whilst sucrase activity was unaffected.
Neg (unaffected) Regulation (unaffected) of whilst sucrase
4) Confidence 0.04 Published 2000 Journal J. Pharm. Pharmacol. Section Abstract Doc Link 10875545 Disease Relevance 0 Pain Relevance 0.06
Effects of two new alpha-glucosidase inhibitors on glycemic control in patients with insulin-dependent diabetes mellitus.
Regulation (Effects) of alpha-glucosidase associated with diabetes mellitus
5) Confidence 0.03 Published 1986 Journal Klin. Wochenschr. Section Title Doc Link 3520133 Disease Relevance 0.41 Pain Relevance 0.12
Direct addition of glucose to islet homogenates showed a suppressive effect on alpha-glucosidase activity at pH 4.0 and 5.0.
Regulation (effect) of alpha-glucosidase
6) Confidence 0.02 Published 1993 Journal Pharmacology Section Abstract Doc Link 8441762 Disease Relevance 0 Pain Relevance 0.07
Mean and median values of SIs for each stripe type are reported in Table 2.
Regulation (values) of SIs
7) Confidence 0.01 Published 2009 Journal Journal of Neurophysiology Section Body Doc Link PMC2775374 Disease Relevance 0 Pain Relevance 0

General Comments

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