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Context Info
Confidence 0.59
First Reported 1982
Last Reported 2006
Negated 2
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 4.79
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
bone marrow 1
urine 1
Salpa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 1 98.08 Very High Very High Very High
abdominal pain 1 95.60 Very High Very High Very High
Pain 12 93.92 High High
Pain score 2 93.04 High High
Osteoarthritis 1 90.68 High High
rheumatoid arthritis 1 90.04 High High
spinal inflammation 1 89.00 High High
headache 1 87.00 High High
Analgesic 4 50.00 Quite Low
Disease Link Frequency Relevance Heat
Recurrence 3 99.76 Very High Very High Very High
Cholangitis 2 99.12 Very High Very High Very High
INFLAMMATION 1 98.08 Very High Very High Very High
Disease 8 98.04 Very High Very High Very High
Vomiting 3 96.48 Very High Very High Very High
Abdominal Pain 1 95.60 Very High Very High Very High
Metastasis 4 94.76 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 94.64 High High
Pain 10 93.92 High High
Sclerosing Cholangitis 2 92.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Benoxaprofen and its effect on serum alkaline phosphatase: a review.
Regulation (effect) of serum alkaline phosphatase
1) Confidence 0.59 Published 1982 Journal Eur J Rheumatol Inflamm Section Title Doc Link 7044796 Disease Relevance 0.37 Pain Relevance 0.23
Serum alkaline phosphatase levels, however, remained essentially unchanged.
Neg (unchanged) Regulation (unchanged) of Serum alkaline phosphatase
2) Confidence 0.44 Published 1995 Journal Am. J. Med. Section Body Doc Link 7503081 Disease Relevance 0.13 Pain Relevance 0
The primary efficacy end point was the percent change in serum alkaline phosphatase.
Regulation (change) of serum alkaline phosphatase
3) Confidence 0.26 Published 1996 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 8772558 Disease Relevance 0.44 Pain Relevance 0.09
Marked elevation of serum alkaline phosphatase levels and lesser changes in hepatic aminotransferase levels are common.
Regulation (changes) of serum alkaline phosphatase
4) Confidence 0.08 Published 1987 Journal Ann. Intern. Med. Section Abstract Doc Link 3548523 Disease Relevance 1.53 Pain Relevance 0.10
Average values of Hb, WBC, serum alkaline phosphatase and calcium did not differ between patients with positive or negative bone marrow biopsy. 86 patients were diagnosed to have bone metastases and 35 more patients were diagnosed within a year following the biopsy.
Regulation (values) of serum alkaline phosphatase in bone marrow associated with metastasis
5) Confidence 0.08 Published 1982 Journal Acta Haematol. Section Abstract Doc Link 6812351 Disease Relevance 0.90 Pain Relevance 0.33
Additional independent determinants of relapse were nadir value of serum alkaline phosphatase activity after treatment, number of previous therapies, and number of affected bones.
Regulation (value) of serum alkaline phosphatase associated with recurrence
6) Confidence 0.06 Published 2003 Journal Bone Section Abstract Doc Link 14623059 Disease Relevance 0.87 Pain Relevance 0.27
No significant changes were observed in serum alkaline phosphatase, serum osteocalcin, urine hydroxyproline, and urine pyridinoline or deoxypyridinoline.
Neg (No) Regulation (changes) of serum alkaline phosphatase in urine
7) Confidence 0.03 Published 1994 Journal Calcif. Tissue Int. Section Abstract Doc Link 8118746 Disease Relevance 0.55 Pain Relevance 0.17
RESULTS: It was established that in the course of pamidronate infusion therapy BE levels remained constant, whereas the values in serum alkaline phosphatase and pain intensity scores were significantly reduced.
Regulation (values) of serum alkaline phosphatase
8) Confidence 0.01 Published 2006 Journal Neuro Endocrinol. Lett. Section Body Doc Link 16891991 Disease Relevance 0 Pain Relevance 0

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