INT37601

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 1986
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 3.70
Pain Relevance 3.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptprs) cell adhesion (Ptprs)
Ptprs (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 56 99.80 Very High Very High Very High
Pain 19 99.46 Very High Very High Very High
Inflammation 56 97.56 Very High Very High Very High
Glutamate receptor 8 96.68 Very High Very High Very High
nMDA receptor 21 93.96 High High
abdominal pain 3 92.80 High High
Glutamate 2 92.00 High High
Chronic pancreatitis 6 86.96 High High
cytokine 24 84.88 Quite High
Hippocampus 34 73.36 Quite High
Disease Link Frequency Relevance Heat
Pain 16 99.46 Very High Very High Very High
INFLAMMATION 62 97.56 Very High Very High Very High
Abdominal Pain 3 92.80 High High
Cognitive Disorder 12 90.88 High High
Injury 6 90.56 High High
Disease 59 89.92 High High
Pancreatitis 6 86.96 High High
Apoptosis 3 86.48 High High
Pheochromocytoma 32 85.04 High High
Stress 4 82.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Long-term pain relief was not related to PTP decrease, PTP after operation, type of operation, or patency of anastomosis as seen by endoscopic retrograde pancreaticography.
Negative_regulation (decrease) of PTP associated with pain
1) Confidence 0.42 Published 1986 Journal Pancreas Section Abstract Doc Link 3562446 Disease Relevance 0.68 Pain Relevance 0.68
Long-term pain relief was not related to PTP decrease, PTP after operation, type of operation, or patency of anastomosis as seen by endoscopic retrograde pancreaticography.
Negative_regulation (decrease) of PTP associated with pain
2) Confidence 0.42 Published 1986 Journal Pancreas Section Abstract Doc Link 3562446 Disease Relevance 0.68 Pain Relevance 0.68
PTP decreased significantly in both groups after drainage.
Negative_regulation (decreased) of PTP
3) Confidence 0.36 Published 1986 Journal Pancreas Section Abstract Doc Link 3562446 Disease Relevance 0.69 Pain Relevance 0.69
We have previously described a PTPH1-KO mouse, generated by replacing the PTP catalytic and the PDZ domain with a LacZ neomycin cassette.
Negative_regulation (replacing) of PTP
4) Confidence 0.20 Published 2008 Journal Behav Brain Funct Section Abstract Doc Link PMC2531118 Disease Relevance 0.17 Pain Relevance 0.07
Therefore, an increased NR2A/NR2B ratio is likely to result in a higher threshold for LTP induction, which could explain the reduction of PTP and LTP.
Negative_regulation (reduction) of PTP associated with long-term potentiation
5) Confidence 0.20 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1892123 Disease Relevance 0.14 Pain Relevance 0.59
In the present study, we found that neonatal exposure to BDE-47 causes developmental effects consisting of a reduction of PTP and LTP, as well as specific reductions of key post-synaptic proteins involved in glutamate receptor signaling.
Negative_regulation (reduction) of PTP associated with glutamate receptor and long-term potentiation
6) Confidence 0.15 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1892123 Disease Relevance 0.09 Pain Relevance 0.13
Further, co-treatment with a PTP inhibitor [potassium bisperoxo (1,10-phenanthroline oxovanadate; phen)] and A?
Negative_regulation (inhibitor) of PTP
7) Confidence 0.13 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2366070 Disease Relevance 0.38 Pain Relevance 0.17
This is exemplified by the fact that co-treatment with the PTP inhibitor phen and A?
Negative_regulation (inhibitor) of PTP
8) Confidence 0.12 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2366070 Disease Relevance 0.88 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox