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Context Info
Confidence 0.01
First Reported 1987
Last Reported 1987
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.59

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peptidase activity (CNDP1) extracellular region (CNDP1)
Anatomy Link Frequency
liver 2
CNDP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 12 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Toxicity 3 81.96 Quite High
Hepatotoxicity 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In non-pretreated hamsters, single doses of acetaminophen (200-400 mg/kg i.p.) caused elevations in serum alanine aminotransferase and sorbitol dehydrogenase activities in a dose-related manner. 3-Methylcholanthrene significantly potentiated, while phenobarbital significantly reduced acetaminophen-induced elevations in serum liver enzyme activities.
Negative_regulation (reduced) of Positive_regulation (elevations) of serum liver enzyme in liver associated with paracetamol
1) Confidence 0.01 Published 1987 Journal Toxicology Section Abstract Doc Link 3564056 Disease Relevance 0.22 Pain Relevance 0.59

General Comments

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