INT37746

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Context Info
Confidence 0.53
First Reported 1987
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.90
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Sdcbp) cytoplasm (Sdcbp)
Anatomy Link Frequency
plasma 2
liver 2
Sdcbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cocaine 3 99.72 Very High Very High Very High
ischemia 26 99.66 Very High Very High Very High
Morphine 4 99.32 Very High Very High Very High
Codeine 4 98.68 Very High Very High Very High
cytokine 9 77.04 Quite High
Catecholamine 1 59.68 Quite High
Inflammation 10 55.60 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 23 99.66 Very High Very High Very High
Injury 46 98.56 Very High Very High Very High
Stress 21 76.72 Quite High
Fever 1 69.40 Quite High
INFLAMMATION 10 55.60 Quite High
Disorder Of Lipid Metabolism 28 50.00 Quite Low
Death 2 48.84 Quite Low
Alcoholic Liver Diseases 9 7.20 Low Low
Body Weight 7 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The apparent antioxidative nature of morphine sulfate was also observed in its effects on induced and noninduced MDA production, both cocaine hydrochloride and codeine phosphate stimulated MDA production by about 20% in the absence of any inducers.
Regulation (effects) of Gene_expression (production) of MDA associated with codeine, cocaine and morphine
1) Confidence 0.53 Published 1987 Journal Biochem. Med. Metab. Biol. Section Abstract Doc Link 3593597 Disease Relevance 0 Pain Relevance 0.71
Effects of quercetin on levels of GSH and MDA in rats with ethanol-induced liver injury
Regulation (Effects) of Gene_expression (levels) of MDA in liver associated with injury
2) Confidence 0.04 Published 2010 Journal Pharmacognosy Magazine Section Body Doc Link PMC2900062 Disease Relevance 0.31 Pain Relevance 0.03
In the present investigation, ischemia and I/R did not change the plasma and renal levels of MDA and NOx, and according to the pathophysiology of I/R, these results can be due to reperfusion insufficient time.
Neg (not) Regulation (change) of Gene_expression (levels) of MDA in plasma associated with ischemia
3) Confidence 0.04 Published 2010 Journal Scand J Trauma Resusc Emerg Med Section Body Doc Link PMC2913934 Disease Relevance 0.32 Pain Relevance 0.20
In the CF group, there were no differences in MDA levels regardless of exercise, but in the C group, MDA levels of DE were significantly higher than those of BE and AE.
Neg (no) Regulation (differences) of Gene_expression (levels) of MDA
4) Confidence 0.03 Published 2010 Journal Nutrition Research and Practice Section Body Doc Link PMC2933445 Disease Relevance 0.27 Pain Relevance 0.06

General Comments

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