INT37780

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Context Info
Confidence 0.26
First Reported 1987
Last Reported 1998
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.36
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PSMB5) nucleoplasm (PSMB5) peptidase activity (PSMB5)
small molecule metabolic process (PSMB5) nucleus (PSMB5) cellular nitrogen compound metabolic process (PSMB5)
Anatomy Link Frequency
chest 1
PSMB5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 5 95.04 Very High Very High Very High
Percutaneous transluminal coronary angioplasty 3 90.20 High High
Thoracotomy 2 86.48 High High
Disease Link Frequency Relevance Heat
Myocardial Infarction 10 98.40 Very High Very High Very High
Angina 2 95.04 Very High Very High Very High
Cv General 3 Under Development 3 91.32 High High
Infarction 2 84.56 Quite High
Injury 1 74.28 Quite High
Coronary Artery Disease 1 68.80 Quite High
Emergencies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Routine coronary angiography subjects had no significant change in MB2/MB1.
Neg (no) Regulation (change) of MB1
1) Confidence 0.26 Published 1994 Journal Clin. Chem. Section Abstract Doc Link 8013097 Disease Relevance 0.22 Pain Relevance 0.28
The storage of serum at 4 degrees C does not influence the MB2/MB1 ratios, whereas storage at 20 degrees C changes them significantly.
Neg (not) Regulation (influence) of MB1
2) Confidence 0.19 Published 1998 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 9587170 Disease Relevance 0.49 Pain Relevance 0.18
Time to first increased value of MB2/MB1 ratio and MB2 isoform was earlier in comparison to that for CK-MB mass concentration and similar to that for myoglobin, a marker that, however, lacks specificity.
Regulation (value) of MB1
3) Confidence 0.12 Published 1995 Journal J. Clin. Lab. Anal. Section Abstract Doc Link 8587003 Disease Relevance 0.06 Pain Relevance 0.06
Using an electrophoretic method, the changes in the catalytic activities of three CK-MM isoforms (MM1, MM2, MM3) and two CK-MB isoforms (MB1, MB2) in the serum of 13 patients with acute myocardial infarction (AMI) have been monitored for 3 days after the onset of chest pain.
Regulation (changes) of MB1 in chest associated with angina and myocardial infarction
4) Confidence 0.04 Published 1987 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 3602911 Disease Relevance 0.59 Pain Relevance 0.10

General Comments

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