INT37950

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Context Info
Confidence 0.44
First Reported 1987
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.24
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (PDSS1)
Anatomy Link Frequency
cochlea 1
teeth 1
PDSS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain threshold 7 100.00 Very High Very High Very High
Neuritis 1 91.68 High High
anesthesia 1 89.68 High High
Pain 2 77.84 Quite High
Disease Link Frequency Relevance Heat
Pain 9 100.00 Very High Very High Very High
Optic Neuritis 1 91.68 High High
Diabetes Mellitus 3 90.68 High High
Leber Hereditary Optic Atrophy 5 89.96 High High
Disease 8 89.40 High High
Hypoxia 1 84.92 Quite High
Aging 2 65.84 Quite High
Lifespan 1 12.00 Low Low
Mitochondrial Disorders 9 5.00 Very Low Very Low Very Low
Deafness 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These complex III damages affects, more specifically, the CoQ binding sites, thus upsetting the proton pump Q cycle and, finally, Oxidative Phosphorylation (OXPHOS) coupling (Figure 2) [2,9].
Regulation (affects) of CoQ
1) Confidence 0.44 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2409300 Disease Relevance 0.43 Pain Relevance 0.09
The TPT changes in these teeth ranged from -43 to +21% of their baseline level.
Regulation (changes) of TPT in teeth associated with pain threshold
2) Confidence 0.24 Published 1998 Journal J Oral Rehabil Section Abstract Doc Link 9781861 Disease Relevance 0.73 Pain Relevance 0.73
Additional observations for other odd-order intermodulation DPs at the 3f1-2f2 and 2f2-f1 frequencies suggested that the basic attributes of the acoustic DPs were similarly affected by systematic manipulation of the basic parameters of the primary tones and the general metabolic state of the cochlea.
Regulation (affected) of DPs in cochlea
3) Confidence 0.09 Published 1987 Journal Hear. Res. Section Abstract Doc Link 3654388 Disease Relevance 0.08 Pain Relevance 0.09

General Comments

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