INT38065

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Context Info
Confidence 0.03
First Reported 1987
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.26
Pain Relevance 3.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Sfat (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 17 100.00 Very High Very High Very High
Morphine 12 100.00 Very High Very High Very High
Equianalgesic 2 99.58 Very High Very High Very High
Cancer pain 2 99.56 Very High Very High Very High
Analgesic 4 99.02 Very High Very High Very High
Pain 4 96.72 Very High Very High Very High
Bile 3 90.52 High High
analgesia 4 72.64 Quite High
tolerance 2 58.12 Quite High
Opioid 2 53.44 Quite High
Disease Link Frequency Relevance Heat
Cancer Pain 2 99.56 Very High Very High Very High
Hepatotoxicity 3 98.28 Very High Very High Very High
Pain 4 96.72 Very High Very High Very High
Cancer 4 92.56 High High
Targeted Disruption 1 88.88 High High
Sleep Disorders 2 61.52 Quite High
Constipation 2 61.00 Quite High
Vomiting 2 60.16 Quite High
Reprotox - General 2 2 49.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No differences were found in the biliary excretion of APAP, APAP-sulfate, and APAP-glutathione between Mrp3+/+ and Mrp3-/- mice.
Localization (excretion) of APAP-sulfate associated with paracetamol
1) Confidence 0.03 Published 2005 Journal Hepatology Section Abstract Doc Link 16250050 Disease Relevance 0.19 Pain Relevance 1.32
Initially, all patients were converted from the prestudy analgesic regimen to an equianalgesic amount of immediate-release morphine sulfate (IRMS) on a q4h dose schedule that was in turn titrated to the level of adequate pain relief.
Localization (release) of sulfate associated with pain, analgesic, equianalgesic and morphine
2) Confidence 0.02 Published 1987 Journal J Clin Pharmacol Section Abstract Doc Link 3680567 Disease Relevance 0.52 Pain Relevance 1.12
Management of cancer pain with oral controlled-release morphine sulfate.
Localization (release) of sulfate associated with cancer pain and morphine
3) Confidence 0.02 Published 1987 Journal J Clin Pharmacol Section Title Doc Link 3680567 Disease Relevance 0.55 Pain Relevance 1.26

General Comments

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