INT38119

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Context Info
Confidence 0.65
First Reported 1987
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 0.74
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (TUBB4A) cytosol (TUBB4A) structural molecule activity (TUBB4A)
cytoskeleton (TUBB4A) cilium (TUBB4A) GTPase activity (TUBB4A)
Anatomy Link Frequency
cleavage 2
colostrum 1
TUBB4A (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 9 99.68 Very High Very High Very High
opioid receptor 1 99.00 Very High Very High Very High
Opioid 4 98.52 Very High Very High Very High
Opioid receptor 1 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Food Hypersensitivity 4 97.28 Very High Very High Very High
Lung Cancer 1 83.68 Quite High
INFLAMMATION 2 78.88 Quite High
Hypersensitivity 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The gene sequence of a human beta-casomorphin-5, including plasmid insertion and fusion protein expression and cleavage instrumentary, has been synthesized by a manual phosphoramidite procedure and cloned in a bacterial system.
Gene_expression (synthesized) of beta-casomorphin-5 in cleavage
1) Confidence 0.65 Published 1987 Journal Nucleic Acids Symp. Ser. Section Abstract Doc Link 3697133 Disease Relevance 0 Pain Relevance 0.10
Synthesis and cloning of a human beta-casomorphin-5 gene.
Gene_expression (Synthesis) of beta-casomorphin-5
2) Confidence 0.65 Published 1987 Journal Nucleic Acids Symp. Ser. Section Title Doc Link 3697133 Disease Relevance 0 Pain Relevance 0.10
The gene sequence of a human beta-casomorphin-5, including plasmid insertion and fusion protein expression and cleavage instrumentary, has been synthesized by a manual phosphoramidite procedure and cloned in a bacterial system.
Gene_expression (expression) of beta-casomorphin-5 in cleavage
3) Confidence 0.56 Published 1987 Journal Nucleic Acids Symp. Ser. Section Abstract Doc Link 3697133 Disease Relevance 0 Pain Relevance 0.10
The aim of this study was to determine the beta-casomorphin-5 and -7 (BCMs) in colostrum and milk of 12 breast-feeding women with a history and clinical manifestation of food allergy.
Spec (determine) Gene_expression (determine) of beta-casomorphin-5 in colostrum associated with food hypersensitivity
4) Confidence 0.39 Published 2008 Journal Pediatr Allergy Immunol Section Abstract Doc Link 18208459 Disease Relevance 0.50 Pain Relevance 0.07
Two analogues of bovine beta-casomorphin-7 and beta-casomorphin-5 containing a beta-homo phenylalanine in substitution of the phenylalanine in position 3 were synthesised and tested for their mu-opioid receptor affinity.
Gene_expression (synthesised) of beta-casomorphin-5 associated with opioid receptor
5) Confidence 0.04 Published 2000 Journal Bioorg. Med. Chem. Lett. Section Abstract Doc Link 10866377 Disease Relevance 0 Pain Relevance 0.12
NSAIDs suppressed the expression of chymotrypsin-like catalytic subunits (beta5, LMP7, and LMP2), but did not directly block enzymatic activity, to inhibit proteasome activity.
Gene_expression (expression) of beta5 associated with cinod
6) Confidence 0.02 Published 2002 Journal Mol. Pharmacol. Section Abstract Doc Link 12435820 Disease Relevance 0.24 Pain Relevance 0.73

General Comments

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