INT38217

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Context Info
Confidence 0.38
First Reported 1981
Last Reported 1986
Negated 1
Speculated 6
Reported most in Abstract
Documents 2
Total Number 8
Disease Relevance 0.56
Pain Relevance 4.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk, Avp) signal transduction (Avp) extracellular space (Avp)
response to stress (Avp) signal transducer activity (Avp)
Anatomy Link Frequency
lobes 4
posterior pituitary 2
Penk (Rattus norvegicus)
Avp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 38 100.00 Very High Very High Very High
Dopamine 10 100.00 Very High Very High Very High
Catecholamine 4 94.48 High High
Intracerebroventricular 1 82.68 Quite High
antagonist 3 75.04 Quite High
narcan 6 68.80 Quite High
Opioid 2 66.64 Quite High
opiate 8 64.56 Quite High
Disease Link Frequency Relevance Heat
Hypertension 6 97.92 Very High Very High Very High
Heart Rate Under Development 1 79.32 Quite High
Volume Depletion And Dehydration 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Vasopressin release does not contribute to pressor action of enkephalin in SHR.
enkephalin Neg (not) Regulation (contribute) of Localization (release) of Vasopressin associated with enkephalin
1) Confidence 0.38 Published 1981 Journal Hypertension Section Title Doc Link 7309204 Disease Relevance 0.39 Pain Relevance 0.95
Enkephalins are found in the posterior pituitary, can alter vasopressin secretion, and have greater pressor effects in spontaneously hypertensive rats (SHR) than in Wistar-Kyoto (WKY) rats.
Enk Regulation (alter) of Localization (secretion) of vasopressin in posterior pituitary associated with hypertension and enkephalin
2) Confidence 0.29 Published 1986 Journal Am. J. Physiol. Section Abstract Doc Link 3717373 Disease Relevance 0.17 Pain Relevance 0.26
This study examines the effect of leu-enkephalin on K+, veratridine and isoproterenol stimulation of vasopressin (AVP) release from perifused neurointermediate pituitaries of rats.
leu-enkephalin Spec (examines) Regulation (effect) of Localization (release) of vasopressin associated with enkephalin
3) Confidence 0.27 Published 1984 Journal Neuroendocrinology Section Abstract Doc Link 6096748 Disease Relevance 0 Pain Relevance 0.40
This study examines the effect of leu-enkephalin on K+, veratridine and isoproterenol stimulation of vasopressin (AVP) release from perifused neurointermediate pituitaries of rats.
leu-enkephalin Spec (examines) Regulation (effect) of Localization (release) of vasopressin associated with enkephalin
4) Confidence 0.20 Published 1984 Journal Neuroendocrinology Section Abstract Doc Link 6096748 Disease Relevance 0 Pain Relevance 0.40
This study examines the effect of leu-enkephalin on K+, veratridine and isoproterenol stimulation of vasopressin (AVP) release from perifused neurointermediate pituitaries of rats.
leu-enkephalin Spec (examines) Regulation (effect) of Localization (release) of AVP associated with enkephalin
5) Confidence 0.20 Published 1984 Journal Neuroendocrinology Section Abstract Doc Link 6096748 Disease Relevance 0 Pain Relevance 0.40
This study examines the effect of leu-enkephalin on K+, veratridine and isoproterenol stimulation of vasopressin (AVP) release from perifused neurointermediate pituitaries of rats.
leu-enkephalin Spec (examines) Regulation (effect) of Localization (release) of AVP associated with enkephalin
6) Confidence 0.20 Published 1984 Journal Neuroendocrinology Section Abstract Doc Link 6096748 Disease Relevance 0 Pain Relevance 0.40
We investigated the effects of dopamine, met-enkephalin and leu-enkephalin on basal and ouabain-stimulated release of oxytocin and vasopressin from isolated neurointermediate lobes.
leu-enkephalin Spec (investigated) Regulation (effects) of Localization (release) of vasopressin in lobes associated with dopamine and enkephalin
7) Confidence 0.04 Published 1984 Journal Exp Brain Res Section Abstract Doc Link 6090193 Disease Relevance 0 Pain Relevance 0.82
We investigated the effects of dopamine, met-enkephalin and leu-enkephalin on basal and ouabain-stimulated release of oxytocin and vasopressin from isolated neurointermediate lobes.
met-enkephalin Spec (investigated) Regulation (effects) of Localization (release) of vasopressin in lobes associated with dopamine and enkephalin
8) Confidence 0.04 Published 1984 Journal Exp Brain Res Section Abstract Doc Link 6090193 Disease Relevance 0 Pain Relevance 0.82

General Comments

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