INT38285

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Context Info
Confidence 0.36
First Reported 1986
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 3.32
Pain Relevance 3.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SCLY) lyase activity (SCLY) cellular amino acid metabolic process (SCLY)
cytoplasm (SCLY)
Anatomy Link Frequency
hearts 2
muscle 1
SCLY (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 213 100.00 Very High Very High Very High
lidocaine 28 99.84 Very High Very High Very High
Fibrositis 147 99.40 Very High Very High Very High
rheumatoid arthritis 4 90.28 High High
backache 17 86.72 High High
ischemia 4 67.92 Quite High
Lasting pain 8 62.88 Quite High
central sensitization 2 57.72 Quite High
nociceptor 2 56.80 Quite High
dysesthesia 4 30.36 Quite Low
Disease Link Frequency Relevance Heat
Pain 215 100.00 Very High Very High Very High
Bradycardia 36 100.00 Very High Very High Very High
Fibromyalgia 147 99.40 Very High Very High Very High
Hypotension 8 96.24 Very High Very High Very High
Rheumatoid Arthritis 4 90.28 High High
Stress 100 88.60 High High
Low Back Pain 17 86.72 High High
Complex Regional Pain Syndromes 2 84.20 Quite High
Injury 7 82.96 Quite High
Cv General 2 Under Development 4 73.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the remaining 10 experiments, the ventricular SCL was increased from 401 +/- 22 to 491 +/- 26 ms after a cumulative dose of 8.8 +/- 0.7 mg/kg of lidocaine.
Positive_regulation (increased) of SCL associated with lidocaine
1) Confidence 0.36 Published 1986 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 3730931 Disease Relevance 0.14 Pain Relevance 0.51
Both lidocaine and verapamil increased the SCL of hearts in which the enhanced ventricular rhythm persisted.
Positive_regulation (increased) of SCL in hearts associated with lidocaine
2) Confidence 0.36 Published 1986 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 3730931 Disease Relevance 0.11 Pain Relevance 0.63
In the presence of verapamil, given as a cumulative dose of 0.60 +/- 0.11 mg/kg, the ventricular SCL was increased from 401 +/- 33 to 482 +/- 64 ms (n = 9).
Positive_regulation (increased) of SCL
3) Confidence 0.36 Published 1986 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 3730931 Disease Relevance 0.13 Pain Relevance 0.61
Analysis of variance showed that only the increase in SCL by lidocaine in 48-h infarcted hearts was statistically significant.
Positive_regulation (increase) of SCL in hearts associated with lidocaine
4) Confidence 0.36 Published 1986 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 3730931 Disease Relevance 0.05 Pain Relevance 0.61
The somatic score of the HSCL was oriented on physical complaints and shows the level of a patientÂ’s perception of his/her physical state.
Positive_regulation (oriented) of HSCL
5) Confidence 0.30 Published 2006 Journal Clin Oral Investig Section Body Doc Link PMC1705496 Disease Relevance 0.13 Pain Relevance 0.13
The third largest response pattern of FMS (12.2%) was characterized by elevated SCL reactivity as sympathetic sudomotor reactivity and increased cardiovascular response as sympathetic vasomotor response as well as the FMS specific reduction in muscle tension.
Positive_regulation (elevated) of SCL in muscle associated with fibrositis
6) Confidence 0.05 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526563 Disease Relevance 1.22 Pain Relevance 0.60
The second subgroup (n = 39) showed a high cardiovascular response pattern with elevated DBP, SBP, and HR, a moderate SCL response, and reduced EMG levels.
Positive_regulation (elevated) of SCL associated with bradycardia
7) Confidence 0.03 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526563 Disease Relevance 0.65 Pain Relevance 0.06
When we adjusted for DRI in early pregnancy, R2 increased from 0.26 (model 1) to 0.37 (model 2) and the sum of pain provocation tests and HSCL-25 were no longer significant (p = 0.26 and p = 0.49, respectively) (Table 4).
Positive_regulation (increased) of HSCL-25 associated with pain
8) Confidence 0.01 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2890600 Disease Relevance 0.89 Pain Relevance 0.82

General Comments

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