INT3830

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.67
First Reported 1977
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 27
Total Number 28
Disease Relevance 15.18
Pain Relevance 10.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (FCGR3B) plasma membrane (FCGR3B)
Anatomy Link Frequency
monocytes 4
nerve 2
CD86 1
blood 1
B cells 1
FCGR3B (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 13 99.98 Very High Very High Very High
Acupuncture 56 99.86 Very High Very High Very High
Pain 57 99.80 Very High Very High Very High
Arthritis 884 99.64 Very High Very High Very High
Serotonin 2 99.40 Very High Very High Very High
headache 12 99.16 Very High Very High Very High
rheumatoid arthritis 204 98.96 Very High Very High Very High
algil 6 98.94 Very High Very High Very High
Pain threshold 18 98.92 Very High Very High Very High
analgesia 3 98.82 Very High Very High Very High
Disease Link Frequency Relevance Heat
Nociception 23 100.00 Very High Very High Very High
Cancer 252 99.98 Very High Very High Very High
Pain 54 99.80 Very High Very High Very High
Seronegative Spondarthritis 780 99.64 Very High Very High Very High
Headache 18 99.16 Very High Very High Very High
Rheumatoid Arthritis 223 98.96 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 110 95.92 Very High Very High Very High
Disease 117 93.52 High High
Hypersensitivity 36 91.16 High High
Hypercalcemia 60 88.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, Kramer and colleagues revealed how CD16 activation regulates TNF?
Positive_regulation (activation) of CD16
1) Confidence 0.67 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.06 Pain Relevance 0.10
In this case, a decrease of the RII reflex was observed in BF, together with an increase of both RIII and pain sensation.
Positive_regulation (increase) of RIII associated with nociception and pain
2) Confidence 0.60 Published 1977 Journal Pain Section Abstract Doc Link 876668 Disease Relevance 1.06 Pain Relevance 0.49
Moreover, the administration of amitriptyline, a drug producing analgesia mainly by blocking serotonin uptake, was able to markedly increase the RIII reflex threshold in MIH.
Positive_regulation (increase) of RIII associated with headache, serotonin, endep and analgesia
3) Confidence 0.59 Published 1986 Journal Funct. Neurol. Section Abstract Doc Link 3609872 Disease Relevance 1.65 Pain Relevance 1.69
The ratio RIII,Cu/RIII,Su was lowered to 10% with naphthalene and increased to 110% with lignocaine.
Positive_regulation (increased) of RIII
4) Confidence 0.59 Published 1977 Journal Pain Section Abstract Doc Link 876670 Disease Relevance 0.66 Pain Relevance 0.71
Intravenous injection of acetylsalicylic acid increased only the RIII,Cu threshold and relative pain threshold.
Positive_regulation (increased) of RIII associated with aspirin and pain threshold
5) Confidence 0.59 Published 1977 Journal Pain Section Abstract Doc Link 876670 Disease Relevance 0.65 Pain Relevance 0.72
Fentanyl exposure under the conditions of this study caused a rapid and significant increase in natural killer cell cytotoxicity, which was coincident with an increase in the percentage of CD16(+) and CD8(+) cells in peripheral blood.
Positive_regulation (increase) of CD16 in blood
6) Confidence 0.49 Published 2002 Journal Anesth. Analg. Section Abstract Doc Link 11772808 Disease Relevance 0.15 Pain Relevance 0.30
through the mitogen-activated protein kinase pathway but at the same time, CD16 activation can also limit TNF?
Positive_regulation (activation) of CD16
7) Confidence 0.48 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.13 Pain Relevance 0.15
Activation of CD16 induces TNF?
Positive_regulation (Activation) of CD16
8) Confidence 0.48 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.11 Pain Relevance 0.13
Intriguingly, we found OC arise from circulating CD16+ monocytes in PsA, whereas OC were generated from the CD16- subset in healthy controls.
Positive_regulation (generated) of CD16 in monocytes associated with arthritis
9) Confidence 0.48 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 1.09 Pain Relevance 0.56
Intriguingly, we found OC arise from circulating CD16+ monocytes in PsA, whereas OC were generated from the CD16- subset in healthy controls.
Positive_regulation (circulating) of CD16 in monocytes associated with arthritis
10) Confidence 0.48 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 1.07 Pain Relevance 0.52
The ratio RIII,Cu/RIII,Su was lowered to 10% with naphthalene and increased to 110% with lignocaine.
Positive_regulation (increased) of RIII
11) Confidence 0.45 Published 1977 Journal Pain Section Abstract Doc Link 876670 Disease Relevance 0.66 Pain Relevance 0.71
After three-day culture in plain media, the percentage of CD14+CD16+ increased in both HC and PsA samples (0.32 to 5.94 for Figure 6(a) vs. 6(c), and 2.50 to 3.38 for Figure 6(b) vs. 6(e)), similar to the result after PBMC were cultured in OC-promoting conditions (Figure 2(b)).
Positive_regulation (increased) of CD16 associated with arthritis
12) Confidence 0.45 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.59 Pain Relevance 0.27
These data indicated that OCPs may undergo a transitional differentiation stage (shown by arrow in Figure 2(b)-b) before they develop into mature OC and upregulate CD16 to a maximal level (Figure 2(b)-c).


Positive_regulation (upregulate) of CD16
13) Confidence 0.45 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.20 Pain Relevance 0.10
Our results showed that CD16 upregulation occurred when monocytes were driven into OC but not DC lineage.
Positive_regulation (upregulation) of CD16 in monocytes
14) Confidence 0.45 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.07 Pain Relevance 0
blocks CD16 upregulation on some CD14+ cells, resulting in two distinct CD14+ populations, CD14+CD16+ and CD14+CD16int (indicated by vertical arrows in Figures 6(d) and 6(f)).
Positive_regulation (upregulation) of CD16int
15) Confidence 0.45 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.47 Pain Relevance 0.21
blocks CD16 upregulation on some CD14+ cells, resulting in two distinct CD14+ populations, CD14+CD16+ and CD14+CD16int (indicated by vertical arrows in Figures 6(d) and 6(f)).
Positive_regulation (upregulation) of CD16
16) Confidence 0.45 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875642 Disease Relevance 0.35 Pain Relevance 0.18
A significant correlation between percentage increase in RIII reflex threshold and reduction of PTI was also observed after amitriptyline treatment, indicating that pain reflex may be used for predicting treatment response in migraine.
Positive_regulation (increase) of RIII associated with pain, migraine and endep
17) Confidence 0.40 Published 1986 Journal Funct. Neurol. Section Abstract Doc Link 3609872 Disease Relevance 1.65 Pain Relevance 1.64
These reflexes were used as an index of pain and were recorded in the biceps femoris muscle, elicited by electrical stimulation of the ipsilateral sural nerve (RIII,su) and of the skin in the distal receptive field of this nerve (RIII,Cu).
Positive_regulation (stimulation) of RIII in nerve associated with pain
18) Confidence 0.40 Published 1977 Journal Pain Section Abstract Doc Link 876670 Disease Relevance 0.38 Pain Relevance 0.22
In contrast, pethidine provoked a decrease in the RIII,Su threshold and an increase in RIII,Cu threshold, parallel with an increase in pain threshold sensation.
Positive_regulation (increase) of RIII associated with pain threshold and algil
19) Confidence 0.40 Published 1977 Journal Pain Section Abstract Doc Link 876670 Disease Relevance 0.62 Pain Relevance 0.72
These reflexes were used as an index of pain and were recorded in the biceps femoris muscle, elicited by electrical stimulation of the ipsilateral sural nerve (RIII,su) and of the skin in the distal receptive field of this nerve (RIII,Cu).
Positive_regulation (stimulation) of RIII in nerve associated with pain
20) Confidence 0.40 Published 1977 Journal Pain Section Abstract Doc Link 876670 Disease Relevance 0.45 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox