INT3854

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Context Info
Confidence 0.41
First Reported 1977
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 16
Total Number 16
Disease Relevance 11.14
Pain Relevance 3.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (SCD) endoplasmic reticulum (SCD)
Anatomy Link Frequency
brains 2
lateral 1
neurons 1
lung 1
central nervous system 1
SCD (Homo sapiens)
Pain Link Frequency Relevance Heat
Delta-9-tetrahydrocannabinol 5 100.00 Very High Very High Very High
Central nervous system 3 99.86 Very High Very High Very High
Morphine 6 99.80 Very High Very High Very High
Cannabinoid 13 99.12 Very High Very High Very High
Pain 12 97.92 Very High Very High Very High
anesthesia 13 96.40 Very High Very High Very High
Neurotransmitter 2 96.08 Very High Very High Very High
Cannabinoid receptor 8 93.36 High High
Endocannabinoid 13 86.80 High High
Angina 4 85.40 High High
Disease Link Frequency Relevance Heat
Sickle Cell Anemia 94 100.00 Very High Very High Very High
Myocardial Infarction 80 100.00 Very High Very High Very High
Marinesco Sjogren Syndrome 6 100.00 Very High Very High Very High
Coronary Heart Disease 5 99.76 Very High Very High Very High
Asthma 17 99.56 Very High Very High Very High
Arrhythmia Under Development 8 98.92 Very High Very High Very High
Cardiomyopathy 8 98.80 Very High Very High Very High
Psychosis 48 98.52 Very High Very High Very High
Heart Rate Under Development 35 98.20 Very High Very High Very High
Pain 12 97.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Myocardial degeneration associated with the SCD was also an undeniable factor of the block.
SCD Binding (associated) of associated with marinesco sjogren syndrome
1) Confidence 0.41 Published 1990 Journal Masui Section Abstract Doc Link 2255048 Disease Relevance 0.80 Pain Relevance 0.25
Two barbiturates, pentobarbital and methohexital, were used as general anesthetics to evaluate their interactions with the effects of delta-9-tetrahydrocannabinol (delta-9-THC) on spinal monosynaptic reflexes in cats with transected spinal cords and ischemically destroyed brains.
delta-9-THC Binding (interactions) of in brains associated with delta-9-tetrahydrocannabinol
2) Confidence 0.34 Published 1983 Journal Life Sci. Section Abstract Doc Link 6300596 Disease Relevance 0.08 Pain Relevance 0.21
The association of SCD with coronary disease and ventricular dysrhythmia suggested ventricular fibrillation as a frequent mechanism.
SCD Binding (association) of associated with arrhythmias 2 under development, arrhythmia under development, coronary heart disease and myocardial infarction
3) Confidence 0.31 Published 1977 Journal Arch. Intern. Med. Section Abstract Doc Link 879938 Disease Relevance 1.76 Pain Relevance 0.09
In contrast, there is significant evidence that asthma-like features may be associated with SCD without a diagnosis of asthma, including a higher than expected prevalence of airway hyper-responsiveness and obstructive lung disease.
SCD Binding (associated) of in lung associated with obstructive airway disease, sickle cell anemia and asthma
4) Confidence 0.31 Published 2009 Journal Hematology Am Soc Hematol Educ Program Section Abstract Doc Link 20008181 Disease Relevance 2.92 Pain Relevance 0.13
Two barbiturates, pentobarbital and methohexital, were used as general anesthetics to evaluate their interactions with the effects of delta-9-tetrahydrocannabinol (delta-9-THC) on spinal monosynaptic reflexes in cats with transected spinal cords and ischemically destroyed brains.
delta-9-tetrahydrocannabinol Binding (interactions) of in brains associated with delta-9-tetrahydrocannabinol
5) Confidence 0.26 Published 1983 Journal Life Sci. Section Abstract Doc Link 6300596 Disease Relevance 0.08 Pain Relevance 0.21
On the other hand, the occurrence of SCD associated to training and competitions for athletes is increased by 2.8 times compared to the average relative risk of non-competitive practitioners [20], hence giving rise to the following question: Does sports activity causes sudden death in young people?
SCD Binding (associated) of associated with sudden death and myocardial infarction
6) Confidence 0.21 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2923123 Disease Relevance 0.99 Pain Relevance 0
The active principle of marijuana, Delta9-tetrahydrocannabinol (Delta9-THC), exerts its pharmacological effects by binding to selective receptors present on the membranes of neurons and other cells.
Delta9-THC Binding (binding) of in neurons
7) Confidence 0.17 Published 2004 Journal Neuropharmacology Section Abstract Doc Link 15464150 Disease Relevance 0.21 Pain Relevance 0.34
The data indicated a complex interaction between delta9-THC and morphine-chloralose combination and the tachycardia induced by delta9-THC under this anesthesia may be due to release of epinephrine by a reflexogenic mechanism involving afferent vagi.
delta9-THC Binding (interaction) of associated with heart rate under development, anesthesia and morphine
8) Confidence 0.13 Published 1977 Journal Eur. J. Pharmacol. Section Abstract Doc Link 885163 Disease Relevance 0.26 Pain Relevance 0.53
It has been shown that TWA has high sensitivity and negative predictive value for predicting SCD after myocardial infarction and is also useful for predicting SCD in patients with nonischemic cardiomyopathy.
SCD Binding (predicting) of associated with cardiomyopathy and myocardial infarction
9) Confidence 0.11 Published 2003 Journal Indian Pacing and Electrophysiology Journal Section Abstract Doc Link PMC1513519 Disease Relevance 1.13 Pain Relevance 0
The data indicated a complex interaction between delta9-THC and morphine-chloralose combination and the tachycardia induced by delta9-THC under this anesthesia may be due to release of epinephrine by a reflexogenic mechanism involving afferent vagi.
delta9-THC Binding (interaction) of associated with heart rate under development, anesthesia and morphine
10) Confidence 0.10 Published 1977 Journal Eur. J. Pharmacol. Section Abstract Doc Link 885163 Disease Relevance 0.26 Pain Relevance 0.53
Psychosocial adjustment to SCD and other life events precipitating psychosis in an adolescent with ongoing schizophrenia
SCD Binding (adjustment) of associated with sickle cell anemia, psychosis and schizophrenia
11) Confidence 0.06 Published 2007 Journal Child Adolesc Psychiatry Ment Health Section Body Doc Link PMC1939835 Disease Relevance 1.97 Pain Relevance 0.06
He was diagnosed with SCD for the first time at the age of two during a bone pain crisis.
SCD Binding (diagnosed) of associated with sickle cell anemia and pain
12) Confidence 0.06 Published 2007 Journal Child Adolesc Psychiatry Ment Health Section Body Doc Link PMC1939835 Disease Relevance 0.68 Pain Relevance 0.26
Figure 2 reveals lateral heterogeneity in the calculated deuterium-order parameter values (SCD) when averaged over 10 ns.
SCD Binding (averaged) of in lateral
13) Confidence 0.05 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1808021 Disease Relevance 0 Pain Relevance 0
During the 1990s, transmembranal proteins in the central nervous system (CNS) that recognize the principal compound of marijuana, the delta-9-tetrahydrocannabinol (Delta9-THC) were described.
delta-9-tetrahydrocannabinol Binding (recognize) of in central nervous system associated with delta-9-tetrahydrocannabinol and central nervous system
14) Confidence 0.01 Published 2008 Journal Prog. Neuropsychopharmacol. Biol. Psychiatry Section Abstract Doc Link 18514375 Disease Relevance 0 Pain Relevance 0.30
This review discusses recent progress in cannabinoid research with a focus on the receptors for delta9-THC, their coupling to second messenger responses, and the endogenous lipid cannabimimetic, anandamide.
delta9-THC Binding (coupling) of associated with cannabinoid
15) Confidence 0.00 Published 1998 Journal Neurochem. Res. Section Abstract Doc Link 9566594 Disease Relevance 0 Pain Relevance 0.40
This review discusses recent progress in cannabinoid research with a focus on the receptors for delta9-THC, their coupling to second messenger responses, and the endogenous lipid cannabimimetic, anandamide.
delta9-THC Binding (coupling) of associated with cannabinoid
16) Confidence 0.00 Published 1998 Journal Neurochem. Res. Section Abstract Doc Link 9566594 Disease Relevance 0 Pain Relevance 0.40

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