INT38558

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 1.59
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (DBT) small molecule metabolic process (DBT) transferase activity, transferring acyl groups (DBT)
cellular nitrogen compound metabolic process (DBT) cytoplasm (DBT)
Anatomy Link Frequency
follicles 2
embryo 1
neurons 1
DBT (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 183 100.00 Very High Very High Very High
Calcium channel 28 90.28 High High
Endogenous opioid 2 85.36 High High
conotoxin 4 67.32 Quite High
Bile 22 53.20 Quite High
antagonist 134 23.32 Low Low
corticosteroid 27 5.00 Very Low Very Low Very Low
Kinase C 24 5.00 Very Low Very Low Very Low
pruritus 22 5.00 Very Low Very Low Very Low
endometriosis 21 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Togavirus Infection 5 93.16 High High
Biliary Liver Cirrhosis 150 92.24 High High
Nicotine Addiction 4 91.44 High High
Emergencies 9 88.80 High High
Appendicitis 1 81.60 Quite High
Ileitis 1 80.44 Quite High
Infection 18 77.40 Quite High
Sprains And Strains 5 61.04 Quite High
Spontaneous Abortion 27 58.56 Quite High
Disease 57 58.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Luteal phase levels of E2 and progesterone measured daily were significantly elevated (P less than 0.01) in CC-treated cycles.
Positive_regulation (elevated) of E2
1) Confidence 0.31 Published 1987 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 3782428 Disease Relevance 0 Pain Relevance 0.16
The E2 level was elevated 24-96 hours after injections in both groups with higher levels noted in the abdominal injections (Figure 3).
Positive_regulation (elevated) of E2
2) Confidence 0.18 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2764710 Disease Relevance 0 Pain Relevance 0
In fact, elevated E2 concentration during FSH-treatment was visible in autotransplanted ewes, indicating the presence of functional developing follicles.
Positive_regulation (elevated) of E2 in follicles
3) Confidence 0.08 Published 2008 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2323016 Disease Relevance 0 Pain Relevance 0
Moreover, the concurrent administration of FSH and an aromatase inhibitor resulted in the suppression of the FSH-induced increase in the circulating levels of E2 (by 100%) with no effect noted on either the number of follicles developed or their size relative to control.
Positive_regulation (increase) of E2 in follicles
4) Confidence 0.08 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0 Pain Relevance 0
We believe this is more accurate than looking at a single measurement of E2 e.g. one day of hCG administration [46].
Positive_regulation (measurement) of E2
5) Confidence 0.07 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0.17 Pain Relevance 0
The authors have concluded that increased implantation failure in superovulated rats may result from the accelerated embryo transport resulting from elevated E2/P ratio.
Positive_regulation (elevated) of E2 in embryo
6) Confidence 0.07 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0.15 Pain Relevance 0
E2 potentiation of [Ca2+]i oscillations requires ER?
Positive_regulation (potentiation) of E2
7) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910705 Disease Relevance 0 Pain Relevance 0.34
Similar to the data obtained in neurons from hES cell lines, the non-selective ER agonist E2 and three distinct ER?
Positive_regulation (selective) of E2 in neurons associated with agonist
8) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910705 Disease Relevance 0 Pain Relevance 0.34
The E1-E2 heterodimers dissociate and E1 trimerizes, causing the E2 subunits to move away, permitting clustering of E1 to initiate fusion.
Positive_regulation (causing) of E2
9) Confidence 0.02 Published 2010 Journal Virol J Section Body Doc Link PMC2831882 Disease Relevance 0.21 Pain Relevance 0
This same group of investigators has shown that 2-octynoic acid, which is widely used in the manufacture of perfumes, lipstick and many common food flavorings, have the potential to modify E2 subunit of PDC (PDC-E2) in vivo [74].
Positive_regulation (modify) of E2 subunit
10) Confidence 0.01 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2266722 Disease Relevance 1.06 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox