INT38624

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Context Info
Confidence 0.01
First Reported 1986
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.24
Pain Relevance 1.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) plasma membrane (Oprm1) kinase activity (Insrr)
signal transducer activity (Oprm1)
Oprm1 (Mus musculus)
Insrr (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 4 100.00 Very High Very High Very High
GABA receptor 3 100.00 Very High Very High Very High
Morphine 1 96.04 Very High Very High Very High
tolerance 1 94.72 High High
analgesia 3 92.36 High High
tail-flick 2 89.64 High High
Analgesic 4 85.20 High High
antagonist 4 84.52 Quite High
Enkephalin 4 75.00 Quite High
gABA 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Diarrhoea 2 84.40 Quite High
Convulsion 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest an interaction between laudanosine and the low-affinity GABA receptor, as well as opioid mu 1 and mu 2 receptors.
opioid mu 1 Binding (interaction) of receptor associated with gaba receptor and opioid
1) Confidence 0.01 Published 1994 Journal Brain Res. Section Abstract Doc Link 8069669 Disease Relevance 0.07 Pain Relevance 0.96
Earlier receptor binding studies of compound XI indicated enhanced affinity for the mu receptor and little for the delta receptor.
mu receptor Binding (affinity) of receptor
2) Confidence 0.00 Published 1986 Journal Int. J. Pept. Protein Res. Section Abstract Doc Link 3793369 Disease Relevance 0.16 Pain Relevance 0.34

General Comments

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