INT38648

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Context Info
Confidence 0.37
First Reported 1986
Last Reported 2007
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.50
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Oxt) extracellular region (Oxt) response to stress (Oxt)
cytoplasm (Oxt)
Anatomy Link Frequency
hypothalamus 2
cerebrospinal fluid 2
Oxt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 28 100.00 Very High Very High Very High
narcan 5 100.00 Very High Very High Very High
opiate 2 100.00 Very High Very High Very High
fluoxetine 11 98.60 Very High Very High Very High
agonist 2 97.76 Very High Very High Very High
Nicotine 4 97.12 Very High Very High Very High
Opioid 1 90.80 High High
amygdala 10 84.96 Quite High
cva 1 80.80 Quite High
Endogenous opioid 1 78.00 Quite High
Disease Link Frequency Relevance Heat
Aids-related Complex 3 89.96 High High
Urological Neuroanatomy 7 83.08 Quite High
Hemorrhage 1 80.80 Quite High
Volume Depletion And Dehydration 1 80.32 Quite High
Aggression 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using male Sprague-Dawley rats, we therefore investigated the effect of an opiate receptor antagonist, naloxone (5 mg/kg s.c.), on the plasma concentrations of oxytocin and vasopressin elevated by various pharmacologic stimuli, including histamine (10 mg/kg i.p.), nicotine (0.15 or 1.5 mg/kg i.p.), isoproterenol (30 or 120 micrograms/kg i.m.) and increased [NaCl] in cerebrospinal fluid (CSF; 10 microliter artificial CSF containing 1 M NaCl i.v.t.).
Spec (investigated) Regulation (effect) of Positive_regulation (elevated) of oxytocin in cerebrospinal fluid associated with nicotine, antagonist, narcan and opiate
1) Confidence 0.37 Published 1986 Journal Neuroendocrinology Section Abstract Doc Link 3796791 Disease Relevance 0.16 Pain Relevance 0.63
Because hypothalamic Gz proteins mediate the ACTH and oxytocin responses to 5-HT1A receptor activation, we also determined the effect of fluoxetine on the levels of Gz proteins in the hypothalamus.
Regulation (responses) of Positive_regulation (activation) of oxytocin in hypothalamus associated with fluoxetine
2) Confidence 0.07 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9862759 Disease Relevance 0 Pain Relevance 0.64
Previous studies have demonstrated that neonatal manipulation of OT affects the central production of OT [2] and the number and distribution of ER?
Regulation (affects) of Positive_regulation (manipulation) of OT
3) Confidence 0.04 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC2048512 Disease Relevance 0.34 Pain Relevance 0.34

General Comments

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