INT38737

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Context Info
Confidence 0.68
First Reported 1986
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (TYRP1)
TYRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 4 100.00 Very High Very High Very High
substance P 1 94.88 High High
qutenza 3 89.28 High High
agonist 1 84.88 Quite High
Dopamine 1 81.12 Quite High
Pain 3 75.00 Quite High
antagonist 3 75.00 Quite High
Inflammation 2 75.00 Quite High
Hyperalgesia 1 62.96 Quite High
IPN 3 56.24 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 98.40 Very High Very High Very High
Pain 1 75.00 Quite High
Injury 1 75.00 Quite High
INFLAMMATION 1 75.00 Quite High
Hyperalgesia 1 62.96 Quite High
Inflammatory Pain 3 56.24 Quite High
Post Operative Pain 3 54.48 Quite High
Neuropathic Pain 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the various biologically active peptides tested, the purified enzyme releases efficiently the N-terminal dipeptide moiety from enkephalins, Trp-Met-Asp-Phe-NH2 (CCK4), and Gly-Trp-Met-Asp-Phe-NH2 (CCK5).
Localization (releases) of Trp associated with enkephalin
1) Confidence 0.68 Published 1986 Journal Biochemistry Section Abstract Doc Link 3814577 Disease Relevance 0 Pain Relevance 0.37
The vanilloid receptor 1 (VR1, TRPV1), which is a member of the transient receptor potential (TRP) superfamily, is highly localized on peripheral and central processes of nociceptive afferent fibers.
Localization (localized) of TRP associated with nociception
2) Confidence 0.09 Published 2005 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15837818 Disease Relevance 0.50 Pain Relevance 0.60

General Comments

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