INT38893

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Context Info
Confidence 0.70
First Reported 1985
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 6
Total Number 6
Disease Relevance 2.36
Pain Relevance 1.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CELA1) extracellular region (CELA1)
Anatomy Link Frequency
pancreas 1
brush 1
CELA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 25 98.52 Very High Very High Very High
Bioavailability 1 96.72 Very High Very High Very High
Bile 1 95.56 Very High Very High Very High
Inflammation 3 91.12 High High
Pain 1 86.20 High High
imagery 2 67.44 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 30 99.84 Very High Very High Very High
INFLAMMATION 3 91.12 High High
Cv Unclassified Under Development 2 90.72 High High
Pancreatic Cancer 4 89.88 High High
Disease 3 89.56 High High
Cirrhosis 2 83.08 Quite High
Appetite Loss 1 67.72 Quite High
Necrosis 1 58.04 Quite High
Cicatrix 1 41.28 Quite Low
Adenoma 1 37.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Duodenal secretion and fecal excretion of pancreatic elastase-1 in healthy humans and patients with chronic pancreatitis.
Localization (secretion) of elastase-1 associated with chronic pancreatitis
1) Confidence 0.70 Published 1997 Journal Pancreas Section Title Doc Link 9260205 Disease Relevance 0.44 Pain Relevance 0.47
Duodenal secretion and fecal excretion of pancreatic elastase-1 in healthy humans and patients with chronic pancreatitis.
Localization (excretion) of elastase-1 associated with chronic pancreatitis
2) Confidence 0.62 Published 1997 Journal Pancreas Section Title Doc Link 9260205 Disease Relevance 0.44 Pain Relevance 0.47
Immunocytochemical localization of elastase 1 in human pancreas.
Localization (localization) of elastase 1 in pancreas
3) Confidence 0.47 Published 1995 Journal Histochem. Cell Biol. Section Title Doc Link 7634150 Disease Relevance 0.45 Pain Relevance 0.09
Elastase secretion in pancreatic disease.
Localization (secretion) of Elastase associated with pancreatitis
4) Confidence 0.10 Published 1985 Journal Am. J. Gastroenterol. Section Title Doc Link 3844284 Disease Relevance 0.82 Pain Relevance 0.29
This presystemic metabolism in the gastrointestinal tract is based on luminally secreted enzymes (I) including pepsins, trypsin, chymotrypsin, elastase and carboxypeptidase A/B, on brush border membrane bound enzymes (II) including various carboxypeptidases and aminopeptidases and on cytosolic enzymes (III).
Localization (secreted) of elastase in brush
5) Confidence 0.02 Published 2007 Journal Curr. Drug Metab. Section Abstract Doc Link 17584022 Disease Relevance 0 Pain Relevance 0.13
Trypsinogen and elastase secreted into pancreatic juice were upregulated after a protein-deficient diet relative to a control diet.
Localization (secreted) of elastase
6) Confidence 0.01 Published 2000 Journal Pancreas Section Abstract Doc Link 10975713 Disease Relevance 0.23 Pain Relevance 0.11

General Comments

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