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Context Info
Confidence 0.21
First Reported 1985
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.14
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL36RN) extracellular region (IL36RN)
Anatomy Link Frequency
cartilage 1
IL36RN (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 2 97.88 Very High Very High Very High
epidural 4 96.52 Very High Very High Very High
analgesia 4 96.16 Very High Very High Very High
cINOD 55 93.92 High High
Inflammatory response 1 93.28 High High
Osteoarthritis 51 85.92 High High
cytokine 3 70.88 Quite High
Angina 1 55.28 Quite High
Inflammation 12 53.88 Quite High
Pain 2 53.20 Quite High
Disease Link Frequency Relevance Heat
Cancer 1 99.80 Very High Very High Very High
Necrosis 1 99.52 Very High Very High Very High
Genetic Predisposition To Disease 2 98.96 Very High Very High Very High
Injury 4 98.40 Very High Very High Very High
Low Back Pain 2 97.88 Very High Very High Very High
Chronic Disease 1 96.48 Very High Very High Very High
Fever 4 95.32 Very High Very High Very High
INFLAMMATION 15 92.92 High High
Osteoarthritis 56 85.92 High High
Apoptosis 1 79.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The findings are also consistent with regulation of interleukin-1 release which is independent of adrenal stimulation, cyclic AMP or beta-endorphin, as epidural analgesia prevents postoperative increase of these hormones.
Regulation (regulation) of interleukin-1 associated with epidural and analgesia
1) Confidence 0.21 Published 1985 Journal Acta Chir Scand Section Abstract Doc Link 3872548 Disease Relevance 0.67 Pain Relevance 0.52
Aim of this study is to evaluate the factors influencing the serum levels of Interleukin-1 beta, in a large and representative population.
Regulation (influencing) of Interleukin-1
2) Confidence 0.01 Published 2003 Journal Cytokine Section Abstract Doc Link 12890453 Disease Relevance 0.38 Pain Relevance 0.14
We recently showed a beneficial effect of celecoxib (Celebrex; Pfizer Inc., New York, NY, USA) on normal cartilage under the influence of interleukin-1 and tumour necrosis factor-?
Regulation (influence) of interleukin-1 in cartilage associated with necrosis and cancer
3) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526565 Disease Relevance 0.89 Pain Relevance 0.95
[A meta-analysis on interleukin-1 gene cluster polymorphism and genetic susceptibility for ankylosing spondylitis].
Regulation (meta-analysis) of interleukin-1 gene associated with spinal inflammation and genetic predisposition to disease
4) Confidence 0.01 Published 2007 Journal Zhonghua Yi Xue Za Zhi Section Title Doc Link 17459217 Disease Relevance 0.20 Pain Relevance 0.19

General Comments

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