INT38936

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Context Info
Confidence 0.40
First Reported 1983
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 0.82
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Avp, Crh) extracellular region (Avp, Crh) response to stress (Avp, Crh)
signal transduction (Avp) cytoplasm (Crh) signal transducer activity (Avp)
Anatomy Link Frequency
blood 1
SCN 1
pituitary 1
Avp (Rattus norvegicus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cholecystokinin 1 97.52 Very High Very High Very High
Dynorphin 1 95.72 Very High Very High Very High
depression 29 95.56 Very High Very High Very High
Enkephalin 1 94.72 High High
Morphine 7 92.36 High High
Neuropeptide 4 91.92 High High
corticosteroid 1 60.48 Quite High
Dopamine 5 12.96 Low Low
Serotonin 7 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 35 95.56 Very High Very High Very High
Stress 6 93.72 High High
Nicotine Addiction 1 77.00 Quite High
Affective Disorder 4 48.40 Quite Low
Sprains And Strains 1 42.24 Quite Low
Anxiety Disorder 11 42.16 Quite Low
Hypernatremia 1 32.00 Quite Low
Neurosis 7 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 3 5.00 Very Low Very Low Very Low
Mental Disorders 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interaction of arginine vasopressin and corticotropin releasing factor demonstrated with an improved bioassay.
arginine vasopressin Binding (Interaction) of corticotropin releasing factor
1) Confidence 0.40 Published 1985 Journal Proc. Soc. Exp. Biol. Med. Section Title Doc Link 3873659 Disease Relevance 0.08 Pain Relevance 0.18
These can be classified as (1) peptides co-localized with AVP or OXY with unambiguous osmotic function, including angiotensin II, apelin, corticotropin releasing hormone, and galanin and (2) peptides co-localized with AVP or OXY with an unknown role in osmotic regulation, including cholecystokinin, chromogranin/secretogranin, dynorphin, endothelin-1, enkephalin, ferritin protein, interleukin 6, kininogen, neurokinin B, neuropeptide Y, vasoactive intestinal peptide, pituitary adenylate cyclase-activating polypeptide, TAFA5 protein, thyrotropin releasing hormone, tyrosine hydroxylase, and urocortin.
AVP Binding (with) of corticotropin releasing hormone in pituitary associated with dynorphin, neuropeptide, enkephalin and cholecystokinin
2) Confidence 0.36 Published 2008 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 18773290 Disease Relevance 0 Pain Relevance 0.24
A possible interaction between synthetic ovine corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) was tested in anesthetized and in freely moving rats.
AVP Binding (interaction) of CRF
3) Confidence 0.36 Published 1983 Journal Endocrinology Section Abstract Doc Link 6307672 Disease Relevance 0 Pain Relevance 0.09
Using this assay, we studied CRF-arginine vasopressin (AVP) interactions at doses that were expected to raise systemic peptide concentrations to levels measured in hypophysial portal blood.
AVP Binding (interactions) of CRF in blood
4) Confidence 0.35 Published 1985 Journal Proc. Soc. Exp. Biol. Med. Section Abstract Doc Link 3873659 Disease Relevance 0.09 Pain Relevance 0.17
A possible interaction between synthetic ovine corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) was tested in anesthetized and in freely moving rats.
vasopressin Binding (interaction) of CRF
5) Confidence 0.31 Published 1983 Journal Endocrinology Section Abstract Doc Link 6307672 Disease Relevance 0 Pain Relevance 0.09
The schematic figure illustrates the impaired interaction among the decreased activity of vasopressin neurons (AVP) in the suprachiasmatic nucleus (SCN), the increased activity of corticotropin-releasing hormone (CRH) neurons in the paraventricular nucleus (PVN), the increased release of adrenocorticotropin (ACTH) into the blood stream by the pituitary gland, and the increased release of cortisol by the adrenal gland.
AVP Neg (impaired) Binding (interaction) of corticotropin-releasing hormone in SCN
6) Confidence 0.30 Published 2010 Journal Qual Life Res Section Body Doc Link PMC2977055 Disease Relevance 0.64 Pain Relevance 0.18
A possible interaction between synthetic ovine corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) was tested in anesthetized and in freely moving rats.
vasopressin Binding (interaction) of ovine corticotropin-releasing factor
7) Confidence 0.25 Published 1983 Journal Endocrinology Section Abstract Doc Link 6307672 Disease Relevance 0 Pain Relevance 0.09

General Comments

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