INT38976

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Context Info
Confidence 0.48
First Reported 1985
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mtor) mitochondrion (Mtor) Golgi apparatus (Mtor)
endoplasmic reticulum (Mtor) nucleus (Mtor) kinase activity (Mtor)
Anatomy Link Frequency
nerve 2
Mtor (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 5 98.64 Very High Very High Very High
Spinal cord 2 97.88 Very High Very High Very High
Sciatic nerve 3 76.08 Quite High
Hippocampus 50 28.08 Quite Low
c fibre 1 25.00 Low Low
long-term potentiation 18 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
amygdala 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 1 28.88 Quite Low
Shock 8 5.00 Very Low Very Low Very Low
Amnesia 6 5.00 Very Low Very Low Very Low
Decapitation 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is widely accepted that rapamycin is a highly specific inhibitor of mTOR.
Positive_regulation (accepted) of Negative_regulation (inhibitor) of mTOR
1) Confidence 0.48 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695538 Disease Relevance 0 Pain Relevance 0
Peripheral nerve section results in depletion of fluoride-resistant acid phosphatase (FRAP) from the nerve terminals in the dorsal horn of the spinal cord (Schoenen et al., '68) and this has been used in the past to map the termination field of individual nerves (Rustioni et al., '71; Devor and Claman, '80).
Positive_regulation (results) of Negative_regulation (depletion) of FRAP in nerve associated with dorsal horn and spinal cord
2) Confidence 0.43 Published 1985 Journal J. Comp. Neurol. Section Abstract Doc Link 3880359 Disease Relevance 0 Pain Relevance 0.17
It is widely accepted that rapamycin is a highly specific inhibitor of mTOR.
Positive_regulation (accepted) of Negative_regulation (inhibitor) of rapamycin
3) Confidence 0.42 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695538 Disease Relevance 0 Pain Relevance 0

General Comments

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