INT39005

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 1985
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 4.97
Pain Relevance 2.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FBN1) extracellular region (FBN1) proteinaceous extracellular matrix (FBN1)
Anatomy Link Frequency
dorsal roots 3
spleen 1
amniotic fluid 1
kidney 1
ventral 1
FBN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Demyelination 4 99.90 Very High Very High Very High
Pain 12 98.98 Very High Very High Very High
Sciatica 16 98.16 Very High Very High Very High
analgesia 3 79.28 Quite High
Enkephalin 1 68.80 Quite High
abdominal pain 2 38.72 Quite Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 4 99.90 Very High Very High Very High
Pain 11 98.98 Very High Very High Very High
Nerve Root Compression 16 98.16 Very High Very High Very High
Cadaver 8 92.48 High High
Disorder Of Lipid Metabolism 4 92.08 High High
Hematologic Neoplasms 2 89.08 High High
Sclerosis 2 83.96 Quite High
Nociception 1 81.36 Quite High
Stress 1 80.48 Quite High
Splenomegaly 6 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Purification and characterization of a low molecular mass cysteine proteinase inhibitor from human amniotic fluid.
Negative_regulation (inhibitor) of mass in amniotic fluid
1) Confidence 0.42 Published 1985 Journal Biol. Chem. Hoppe-Seyler Section Title Doc Link 3885972 Disease Relevance 0.07 Pain Relevance 0.07
Histologic and ultrastructural findings in the kidney and spleen raised the likelihood of lecithin-cholesterol acyltransferase (LCAT) deficiency, which was confirmed by the markedly decreased serum LCAT activity and serum LCAT mass.
Negative_regulation (decreased) of mass in kidney
2) Confidence 0.42 Published 2009 Journal Metab. Clin. Exp. Section Abstract Doc Link 19592052 Disease Relevance 0.85 Pain Relevance 0.07
However, there were significantly lower numbers of large MFs per root and significantly thinner myelin sheaths relative to axon size on the indented side compared with those on the normal side in both the ventral and dorsal roots.
Negative_regulation (numbers) of MFs in ventral
3) Confidence 0.37 Published 1995 Journal J. Neurosurg. Section Abstract Doc Link 7616282 Disease Relevance 0.53 Pain Relevance 0.34
There was no evidence found of axonal degeneration, ongoing demyelination, or loss of MFs in either the ventral or dorsal roots in the radiculopathy group on the indented side.
Negative_regulation (loss) of MFs in dorsal roots associated with demyelination and sciatica
4) Confidence 0.37 Published 1995 Journal J. Neurosurg. Section Abstract Doc Link 7616282 Disease Relevance 0.56 Pain Relevance 0.36
In the control group, there were no differences in the morphometric parameters: that is, total transverse fascicular area, total number of small and large MFs, and relationship between myelin thickness and the radius of the axon between the right and left sides in either the ventral or dorsal roots.
Negative_regulation (number) of MFs in dorsal roots
5) Confidence 0.37 Published 1995 Journal J. Neurosurg. Section Abstract Doc Link 7616282 Disease Relevance 0.56 Pain Relevance 0.35
Histologic and ultrastructural findings in the kidney and spleen raised the likelihood of lecithin-cholesterol acyltransferase (LCAT) deficiency, which was confirmed by the markedly decreased serum LCAT activity and serum LCAT mass.
Negative_regulation (decreased) of mass in spleen
6) Confidence 0.14 Published 2009 Journal Metab. Clin. Exp. Section Abstract Doc Link 19592052 Disease Relevance 0.85 Pain Relevance 0.07
After sham treatment, pain thresholds significantly increased, whereas after MFs a slight non-significant decrease in thresholds was found.
Negative_regulation (decrease) of MFs associated with pain
7) Confidence 0.13 Published 1997 Journal Brain Res. Section Abstract Doc Link 9374207 Disease Relevance 0.87 Pain Relevance 1.01
However, there were significantly lower numbers of large MFs per root and significantly thinner myelin sheaths relative to axon size on the indented side compared with those on the normal side in both the ventral and dorsal roots.
Negative_regulation (numbers) of MFs in dorsal roots
8) Confidence 0.13 Published 1995 Journal J. Neurosurg. Section Abstract Doc Link 7616282 Disease Relevance 0.53 Pain Relevance 0.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox