INT39133

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Context Info
Confidence 0.30
First Reported 1985
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.80
Pain Relevance 1.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ace2) extracellular space (Ace2) extracellular region (Ace2)
plasma membrane (Ace2)
Ace2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 24 100.00 Very High Very High Very High
antagonist 3 95.12 Very High Very High Very High
fibrosis 4 17.88 Low Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 42 99.90 Very High Very High Very High
Left Ventricular Hypertrophy 16 99.76 Very High Very High Very High
Hypertrophy 5 98.28 Very High Very High Very High
Coronary Heart Disease 5 97.52 Very High Very High Very High
Cardiovascular Disorder Under Development 1 40.88 Quite Low
Stress 1 20.96 Low Low
Apoptosis 1 20.72 Low Low
Fibrosis 4 17.88 Low Low
Targeted Disruption 1 9.44 Low Low
Heart Rate Under Development 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Li et al.24 have suggested that the LVH in SHR was associated with ACE and ACE2 gene expression cardiac RAS, while aortic hypertrophy was associated with angiotensinogen and ACE2 gene expression of aortic RAS.
ACE2 Binding (associated) of associated with hypertrophy, left ventricular hypertrophy and hypertension
1) Confidence 0.30 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC3020347 Disease Relevance 0.80 Pain Relevance 0
We interpreted this drinking response as being the sum of morphine-induced drinking (following a permissive interaction between morphine and circulating angiotensin I or renin) and captopril-induced drinking (following a captopril-induced increase in circulating renin and angiotensin I levels).
angiotensin I Binding (interaction) of associated with morphine
2) Confidence 0.13 Published 1985 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 3913393 Disease Relevance 0 Pain Relevance 1.01
This result pointed once again to a permissive interaction between morphine and circulating angiotensin I or renin.
angiotensin I Binding (interaction) of associated with morphine
3) Confidence 0.13 Published 1985 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 3913393 Disease Relevance 0 Pain Relevance 0.88

General Comments

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