INT39369

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Context Info
Confidence 0.29
First Reported 1986
Last Reported 2010
Negated 5
Speculated 3
Reported most in Body
Documents 14
Total Number 19
Disease Relevance 16.70
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
superior 1
aqueous humour 1
pupil 1
globe 1
optic nerve 1
NARFL (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 6 97.76 Very High Very High Very High
beta blocker 45 94.92 High High
antagonist 25 86.92 High High
Inflammation 35 85.68 High High
ischemia 9 84.16 Quite High
cytokine 1 80.72 Quite High
chemokine 1 79.60 Quite High
Serotonin 51 71.64 Quite High
cva 12 52.56 Quite High
Pain 24 44.36 Quite Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 1485 100.00 Very High Very High Very High
Glaucoma 386 99.44 Very High Very High Very High
Hypotension 62 97.92 Very High Very High Very High
Open-angle Glaucoma 36 97.60 Very High Very High Very High
Birth Weight 24 97.60 Very High Very High Very High
Conjunctivitis 43 95.68 Very High Very High Very High
Age-related Macular Degeneration 7 92.48 High High
Cataract 52 91.56 High High
Uveitis 17 90.96 High High
Retina Disease 9 90.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Timolol does not have any effect on the outflow mechanism and exerts its effect on IOP by reducing aqueous humour production (Yablonski et al 1978).
IOP Binding (effect) of in aqueous humour associated with ocular hypertension
1) Confidence 0.29 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2698680 Disease Relevance 0.44 Pain Relevance 0.04
We surmise that the decrease of IOP is probably associated with the intensity of the massage of the globe during the surgery.
IOP Binding (associated) of in globe
2) Confidence 0.28 Published 1986 Journal J Pediatr Ophthalmol Strabismus Section Abstract Doc Link 3958879 Disease Relevance 0.23 Pain Relevance 0.10
In addition, Hojs and Pahor12 could not find statistically significant differences in IOP either before or after hemodialysis even though osmolarity changes were present.
IOP Neg (not) Binding (find) of associated with ocular hypertension
3) Confidence 0.16 Published 2006 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2908824 Disease Relevance 1.41 Pain Relevance 0
For patients whose IOP does not respond to latanoprost, adding or switching to FCDT has also been found to be beneficial.
IOP Neg (not) Binding (respond) of associated with ocular hypertension
4) Confidence 0.14 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693974 Disease Relevance 0.94 Pain Relevance 0
Based on information from the PRN regarding the pregnancy (weeks gestation) and the newborn (birth weight, Apgar score and congenital malformations), the children of the full sample will be assigned to a risk profile (i.e.
PRN Binding (information) of associated with birth weight
5) Confidence 0.11 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2978208 Disease Relevance 0.17 Pain Relevance 0
Based on information from the PRN and the establishment of a clear set of criteria, all children at 'high risk' and a random sample of children at 'low risk' will be selected.
PRN Spec (clear) Binding (information) of
6) Confidence 0.11 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2978208 Disease Relevance 0 Pain Relevance 0
The data received from the IVF centres will be linked to the PRN database, which encompasses information regarding mother, pregnancy and newborn.
PRN Binding (linked) of
7) Confidence 0.11 Published 2010 Journal BMC Pediatr Section Body Doc Link PMC2978208 Disease Relevance 0.06 Pain Relevance 0
At the 3-month timeframe, the mean reduction from baseline IOP for patients who were not on a prostaglandin analog was ?
IOP Binding (baseline) of associated with ocular hypertension
8) Confidence 0.08 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2993108 Disease Relevance 0.65 Pain Relevance 0
Mean baseline IOP measured before switching to the replacement therapy with dorzolamideĀ–timolol was 19.4 mmHg and after 4 weeks of treatment on the replacement therapy, a significant additional IOP reduction of ?
IOP Binding (switching) of associated with ocular hypertension
9) Confidence 0.08 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2993108 Disease Relevance 0.77 Pain Relevance 0.08
As IVTA can be considered as a therapeutic approach for a large spectrum of clinical conditions, knowledge of the subsequent IOP response needs to be established, since steroids are associated with IOP increase [4].
IOP Binding (associated) of associated with ocular hypertension
10) Confidence 0.08 Published 2008 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2694598 Disease Relevance 1.26 Pain Relevance 0
Lowering the IOP is recognized to retard or prevent additional damage to the optic nerve.
IOP Binding (recognized) of in optic nerve associated with ocular hypertension
11) Confidence 0.08 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2993108 Disease Relevance 1.33 Pain Relevance 0.03
However, there is no association between the CCT and the PASCAL IOP (r = 0.02, P = 0.84; Figure 2).
PASCAL IOP Neg (no) Binding (association) of associated with ocular hypertension
12) Confidence 0.07 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2909890 Disease Relevance 1.77 Pain Relevance 0
The IOP level did not associate with the flare value and cell counts.
IOP Neg (not) Binding (associate) of associated with ocular hypertension
13) Confidence 0.06 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965576 Disease Relevance 1.59 Pain Relevance 0.34
Linear regression was used to analyze the residual association between the CCT and the difference in Ehlers IOP and PASCAL IOP.
IOP Spec (analyze) Binding (association) of associated with ocular hypertension
14) Confidence 0.05 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2909890 Disease Relevance 1.34 Pain Relevance 0.07
Linear regression was used to analyze the residual association between the CCT and the difference in Ehlers IOP and PASCAL IOP.
PASCAL IOP Spec (analyze) Binding (association) of associated with ocular hypertension
15) Confidence 0.05 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2909890 Disease Relevance 1.36 Pain Relevance 0.07
However, data from human studies conducted after oral or topical administration of ketanserin, in which were determined the variations of IOP, total outflow facility and pupil diameter, demonstrated that the ?
IOP Binding (variations) of in pupil associated with ocular hypertension
16) Confidence 0.05 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2701282 Disease Relevance 0.57 Pain Relevance 0.17
Bimatoprost was superior in IOP lowering to travoprost only during the daytime (0800 and 1200 hours time-points), but latanoprost and travoprost were comparable at all time points (P ?
IOP Binding (lowering) of in superior associated with ocular hypertension
17) Confidence 0.03 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2915861 Disease Relevance 0.59 Pain Relevance 0
The mean IOP peaked from 2 weeks to 1 month postoperatively, and then stabilized over the ensuing months.
IOP Binding (stabilized) of associated with ocular hypertension
18) Confidence 0.02 Published 2009 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2694298 Disease Relevance 1.23 Pain Relevance 0.03
There was no association between preoperative IOP and postoperative BCVA (P=0.361).
IOP Neg (no) Binding (association) of associated with ocular hypertension
19) Confidence 0.02 Published 2010 Journal Indian Journal of Ophthalmology Section Body Doc Link PMC2907031 Disease Relevance 0.99 Pain Relevance 0

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